Presentation Information
[1T07-10]Development of a novel peptide-based inhibitory compound against EML4-ALK by targeting the substrate binding domain of ALK
○Yifan Shi1, Miho Takahashi1, Hiroyuki Hara1, Norihito Shibata2, Mikihiko Naito3, Atsuko Deguchi4,5, Yoshiro Maru5, Kiyotaka Nishikawa1 (1.molecular life/Preventive Medicine Labratory, Faculty of Life and Medical Sciences, Doshisha University, 2.National institute of Health Sciences, Division of biochemistry, 3.Laboratory of Targeted Protein Degradation, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 4.Institute of Advanced Biomedical Engineering and Scicense, Tokyo Women's Medical University, 5.Department of Pharmacology,Tokyo Women's Medical University)
キーテクノロジー：多価型ペプチドライブラリー法
Keywords:
EML4-ALK、TKI耐性変異
ctuj2024@mail4.doshisha.ac.jp
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