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Presentation Information

Session Details

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Program Type

Mechanistic insight of NeuroD1-induced microglia-neuron lineage switch

Once cells differentiate, it has been considered to be difficult to redirect the cells to other lineages. However, the establishment of induced pluripotent cells (iPSCs) with introduction of only a minimum set of genes revealed that reprograming of cells per se is not such a big hurdle. Since then, strategies to directly reprogram somatic cells into desirable ones in different lineages have been investigated extensively. In this symposium, we would like to introduce methods and application of 5 representative artificially generated cells, i.e., induced pluripotent stem (iPS) cells, induced hepatocyte-like cells (iHep) cells, induced neuron-like (iN) cells, induced cardiomyocyte-like (iCM) cells, and induced renal epithetical tubule cells (iRECs).

日本分子生物学会年会

The 41st Annual Meeting of the Molecular Biology Society of Japan

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1S-16-1]Mechanistic insight of NeuroD1-induced microglia-neuron lineage switch

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