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Presentation Information

Session Details

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Program Type

Regulatory T cells convert antigen presenting cells towards a tolerogenic state via CTLA-4-dependent trogocytosis of CD80

Recent studies highlight a novel form of cell-cell communication via various forms of phagocytosis including cell nibbling, or trogocytosis. Cells "share information" by nibbling or taking up whole neighboring cells in distinction from traditional ligand-receptormediated signal transduction. This session will uniquely discuss how this special form of cell-cell communication has established diverse cell functions in phagocytic cells, not just transient reactions to environmental stimuli. The exciting scope of this session will include various forms of phagocytosis in bacteria, immune cells, and their relations to disease pathologies. We will introduce the previously unrecognized importance of phagocytosis in promoting evolution and cell diversity.

日本分子生物学会年会

The 45th Annual Meeting of the Molecular Biology Society of Japan

The 45th Annual Meeting of the Molecular Biology Society of Japan

[1AW-03-6]Regulatory T cells convert antigen presenting cells towards a tolerogenic state via CTLA-4-dependent trogocytosis of CD80

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