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Mitochondrial transcription elongation factor facilitates the transition from RNA synthesis to DNA synthesis at the H-strand replication origin of human mitochondrial DNA

Genomic DNA in nucleus and mitochondria must be inherited properly. However, DNA replication is often compromised by obstacles stems from intrinsic and extrinsic stimuli, leading to genome instability and various diseases including cancer. In this symposium, we will discuss the latest findings on the cellular strategy to maintain genome stability or to tolerate genome stress from the aspect of molecular mechanism and cancer biology, focusing on PrimPol.<br>

日本分子生物学会年会

The 47th Annual Meeting of the Molecular Biology Society of Japan

The 47th Annual Meeting of the Molecular Biology Society of Japan

[1PS-12-05]Mitochondrial transcription elongation factor facilitates the transition from RNA synthesis to DNA synthesis at the H-strand replication origin of human mitochondrial DNA

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