[3P-317]Enhancing the anti-cancer activity of ADC by divalent conjugation of drugs to anti-HER2 antibody using branch linker
○Satoshi Fukuda1, Jumpei Taguchi2, Koji Umezawa3, Miho Hanya2, Tadashi Takimoto4, Toshiko Kitada1, Takashi Niwa2,4,5, Takamitsu Hosoya2,4, Isao Kii1,3(1. Department of Agriculture, Graduate School of Science and Technology, Shinshu University, 2. Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 3. Institute for Biomedical Sciences, Shinshu University, 4. Laboratory for Chemical Biology, RIKEN BDR, 5. Graduate School of Pharmaceutical Sciences, Kyushu University)
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