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Understanding the disease risk of human transposons by population genetics

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Transposons have long been thought to account for approximately 40% of the human genome. However, the Telomere-to-Telomere (T2T) Consortium recently revealed that this proportion reaches 53%. This groundbreaking discovery highlights the “peculiar" symbiotic relationship between humans (and other host organisms) and transposons spanning hundreds of millions of years, heralding a new era of transposon research. What is the true purpose of transposons co-existing in the genome? How have we, as hosts, managed to accommodate, control, and even harness their selfish nature for our benefit? Could transposons hold the potential as a novel modality for drug discovery? In this symposium, researchers exploring transposons from diverse perspectives will come together to share cutting-edge insights and engage in discussions with the audience on these fascinating questions.

日本分子生物学会年会

The 48th Annual Meeting of the Molecular Biology Society of Japan

The 48th Annual Meeting of the Molecular Biology Society of Japan

[1AS-02-04]Understanding the disease risk of human transposons by population genetics

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