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Wed. Dec 3, 2025

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A novel regulation of nuclear proteostasis (protein homeostasis) by cell competition regulator Mahjong (VprBP/DCAF1)

Multicellular systems possess "robustness," the ability to overcome various disturbances and reproducibly create structures with the same shape and function. This concept was proposed by Waddington in the 1940s, but mechanisms ensuring robustness at multicellular levels, which is necessary to understand development and disease prevention, remain unclear. This symposium will introduce the latest understanding on multicellular robustness and will also serve as an opportunity to reconsider robustness.

【E】Multicellular Robustness revisited

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[1AS-03-06]A novel regulation of nuclear proteostasis (protein homeostasis) by cell competition regulator Mahjong (VprBP/DCAF1)

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