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Wed. Dec 3, 2025

Thu. Dec 4, 2025

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Pathogenic mechanism of kidney failure upon dysfunction of a tRNA modification enzyme, CDKAL1

RNA modifications found in various RNA species, including mRNA, tRNA, and rRNA, add new chemical properties to nucleic acids. Disruptions in these modifications have been linked to diseases such as neurological disorders and cancer. In this symposium, we will collectively refer to these modifications as the "RNA epicode" and provide an overview of the latest advancements. Discussions will focus on key areas, including (i) regulatory mechanisms, (ii) roles in physiology and pathology, (iii) detection technologies, and (iv) nucleic acid chemistry and engineering. Through these discussions, we aim to explore new directions for future research.

【J】Physiological functions of RNA Epicodes and their regulation

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[1AS-04-03]Pathogenic mechanism of kidney failure upon dysfunction of a tRNA modification enzyme, CDKAL1

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