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Wed. Dec 3, 2025

Thu. Dec 4, 2025

Fri. Dec 5, 2025

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Single-Cell Transcriptomic Analysis Reveals Aging-Associated Microglial Subpopulations, Their Dynamics, and Disease Relevance

Aging signals and metabolic stress form intricate networks that extend beyond cellular senescence, shaping aging at organ and organismal levels and contributing to the onset and progression of various diseases. Homeostatic mechanisms within cells and molecules are closely tied to aging, immune responses, and cancer, and their failure underlies many pathological conditions. Advances in single-cell analysis, spatial transcriptomics, and proteomics now offer dynamic, multidimensional insights into these complex networks across cells and organs. This symposium convenes researchers investigating aging, disease, and life processes from neuroscience, metabolism, immunology, and genetics perspectives. By exploring innovative studies on the interactions between aging, disease progression, and homeostatic regulation, we aim to enhance our understanding of these interconnected phenomena.

【J】Integrated Understanding of Life, Aging, Disease, and Death Unraveled from the Cellular and Molecular Perspectives

The 48th Annual Meeting of the Molecular Biology Society of Japan

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[1PS-03-04(1P-725)]Single-Cell Transcriptomic Analysis Reveals Aging-Associated Microglial Subpopulations, Their Dynamics, and Disease Relevance

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