Presentation Information
[P-28-01]Identification of the right gene for Child and Adult ADHD: A Systematic Review
*Nor Ellisha Ismail, Shalisah Sharip, Suriati Mohamed Saini, Siti Aishah Sulaiman (Universiti Kebangsaan Malaysia(Malaysia))
Keywords:
Gene,ADHD,Adult,review
Introduction: Attention Deficit and Hyperactivity Disorder (ADHD) is a psychiatric disorder identified in childhood that continues in adulthood that impairing quality of life if not appropriately managed. A lot of research has indicated that DRD4 may be involved in ADHD in children with little information for adult ADHD. Thus, the aim of this review to determine which candidate genes show consistent evidence of association with child as well as adult with ADHD.
Method: We performed a literature search in four databases which are PubMed, Scopus, ScienceDirect and Google Scholar to find pertinent studies for the review. Final papers chosen were 20 child ADHD and 5 adult ADHD from the total of 344 papers in the range of 10 years from 2014 to 2024.
Result: The finding of this review showed that the key genes in ADHD are COMT, LPHN3 and DRD4 genes have direct association with both adult ADHD and child based. The number of children participants are 6,002 individuals, both ADHD patients and control groups across all research. The number of adults participants are 78,926 across the research articles. The number of male and female participants varies.
Conclusion: This genetic review provide insight the significant hereditary component of ADHD across all ages. This information is crucial to that help clinician and researcher developed age appropriate intervention and prevention strategies that enhance quality of life
Method: We performed a literature search in four databases which are PubMed, Scopus, ScienceDirect and Google Scholar to find pertinent studies for the review. Final papers chosen were 20 child ADHD and 5 adult ADHD from the total of 344 papers in the range of 10 years from 2014 to 2024.
Result: The finding of this review showed that the key genes in ADHD are COMT, LPHN3 and DRD4 genes have direct association with both adult ADHD and child based. The number of children participants are 6,002 individuals, both ADHD patients and control groups across all research. The number of adults participants are 78,926 across the research articles. The number of male and female participants varies.
Conclusion: This genetic review provide insight the significant hereditary component of ADHD across all ages. This information is crucial to that help clinician and researcher developed age appropriate intervention and prevention strategies that enhance quality of life