[1S02m-01]Post-transcriptional dysregulation shapes the aging proteome: mechanisms and consequences
○Masaki Takasugi, Naoko Ohtani(Department of Pathophysiology, Osaka Metropolitan University Graduate School of Medicine)
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2024 - 2025
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| Year : | 2024 - 2025 |
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Search Results(4,646)
[1S02m-02]Dysfunction of dopamine in the entorhinal cortex induces associative memory impairment in Alzheimer's disease mouse models
○Kei M. Igarashi(Department of Anatomy & Neurobiology, School of Medicine, University of California, Irvine)
[1S02m-03]Elucidation of the heterogeneity system of mesenchymal stromal cells that support skeletal muscle homeostasis
○Akiyoshi Uezumi(Division of Cell Heterogeneity, Medical Institute of Bioregulation, Kyushu University)
[1S02m-04]Tracing Inflammation and Molecular Changes in the Aging Kidney
○Motoko Yanagita(Department of Nephrology, Graduate School of Medicine, Kyoto University)
[1S02m-05]The roles and mechanisms of cellular senescence
○Eiji Hara(Research Institute for Microbial Diseases, The University of Osaka)
[1S03m-01]The novel function of lipid flux on RORγt-mediated Th17 cell pathogenicity
○Yusuke Endo(KAZUSA DNA RESEARCH INSTITUTE)
[1S03m-02]On the biochemical dialog between immune cells mediating anti-cancer responses
○Sidonia Fagarasan1,2(1.Laboratory for Mucosal Immunity, RIKEN Center for Integrative Medical Sciences, 2.Division of Integrated High-Order Regulatory Systems, Center for Cancer Immunotherapy and Immunobiology, Kyoto University)
[1S03m-03]Immune Evasion Through Mitochondrial Transfer: A "Mitochondrial Hijack" Mechanism
○Yosuke Togashi1,2(1.Department of Tumor Microenvironment, Faculty of Medicine, Dentistry and Pharmaceutical Sciences (Medicine), Okayama University, 2.OKAYAMA UNIVERSITY HOSPITAL, Department of Allergy and Respiratory Medicine)
[1S03m-04]Metabolic Exhaustion in Tumor-Infiltrating T Cells: Role of Active Aldehydes in Glycolysis and FAO Balance
○Kenji Chamoto(Department of Immuno-Oncology PDT, Kyoto University Graduate School of Medicine)
[1S03m-05]Systemic metabolism regulates T cell ferroptosis and functionality
○Di Yu1,2(1.The University of Queensland Frazer Institute, The University of Queensland and Translational Research Institute, 2.Ian Frazer Centre for Children's Immunotherapy Research, Child Health Research Centre, The University of Queensland)
[1S04m-00]Introduction
○Hiromi Hirata(Aoyama Gakuin University)
[1S04m-01]Evolution of egg envelope formation in teleosts based on potential polymerization mechanisms.
○Kaori Sano1, Mai Yabe2, Kana Watanabe2, Shinji Kanda3(1.Faculty of Science, Josai University, 2.Graduate School of Pharmaceutical Sciences, Josai University, 3.Atmosphere and Ocean Research Institute, The University of Tokyo)
[1S04m-02]Modular structure of gametogenesis driving the diversification of reproductive modes
○Mariko Kikuchi1, Yu Ikeda2, Shuji Shigenobu3, Minoru Tanaka1(1.Department of Biological Science, Graduate School of Science, Nagoya University, 2.Department of Biological Science, School of Science, Nagoya University, 3.Trans-Omics Facility, National Institute of Basic Biology)
[1S04m-03]Transplantation of germline stem cells from semelparous salmon into iteroparous rainbow trout alters their function to that of the recipient
○Goro Yoshizaki(Tokyo University of Marine Science and Technology)
[1S04m-04]Ultra-short-lived fish reveals unexpected mechanisms of healthy longevity
○Tohru Ishitani(RIMD, The University of Osaka)
[1S04m-05]Color information generated by a single type of opsin in the zebrafish pineal organ
○Seiji Wada(Aoyama Gakuin University)
[1S04m-06]Uncovering a novel photobiological mechanism through pituitary research in medaka
○Ayaka Fukuda1, Keita Sato2, Shinji Kanda3(1.National Institute for Basic Biology, National Institutes of Natural Sciences, 2.Faculty of Medicine, Dentistry, and Pharmaceutical Science, Okayama University, 3.Atmosphere and Ocean Research Institute, The University of Tokyo)
[1S04m-07]Closing Remarks
[1S05m-01]Toward High-Sensitivity, Whole-Transcript Spatial Transcriptomics
○Akiko Oguchi1,2, Raku Son1,2, Yasuhiro Murakawa1,2(1.Laboratory for Gene Structure and Regulation, RIKEN Center for Integrative Medical Sciences, 2.Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University)
[1S05m-02]Precision Cardiovascular Medicine with Single-cell Analysis
○Seitaro Nomura(The University of Tokyo)
[1S05m-03]Sequence grammar and dynamics of subcellular translation revealed by APEX-Ribo-Seq
○Shintaro Iwasaki1,2(1.Pioneering Research Institute, RIKEN, 2.Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo)
[1S05m-04]Proteomic characterization of the functional impact of co-/post-translational modifications
○Koshi Imami(RIKEN Center for Integrative Medical Sciences)
[1S05m-05]Biophysical Proteomics
○Mikhail Savitski(EMBL)
[1S06m-01]Molecular mechanism of bulk phospholipid transfer for autophagosome formation
○Nobuo N. Noda1,2(1.Institute for Genetic Medicine, Hokkaido University, 2.Institute of Microbial Chemistry)
[1S06m-02]How the lipid transfer protein Atg2 associates with the ER during autophagosome biogenesis
○Hitoshi Nakatogawa(Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo)
[1S06m-03]A phosphorylation-driven functional switch in p62 bodies coordinates autophagic clearance of ubiquitinated proteins
○Masaaki Komatsu(Juntendo University Graduate School of Medicine)
[1S06m-04]Restoration of autophagy defects reverses neuronal dysfunction
○Noboru Mizushima, Tomoya Eguchi(The University of Tokyo)
[1S06m-05]Autophagy networks in the regulation of ER contact sites
○Ivan Dikic1,2(1.Institute of Biochemistry II, Goethe University, 2.Max Planck Institute for Biophysics)
[1S07m-00]Overview talk
○Motohiko Kadoki(Harvard Medical School / Massachusetts General Hospital / Broad Institute of MIT and Harvard)
[1S07m-01]Hints for Revival: Reflections on Thesis Defense, Choosing a Postdoctoral Lab, the Path to Research Independence, and Competitive Research Funding
○Yoji Andrew Minamishima(Department of Biochemistry, Gunma University Graduate School of Medicine)
[1S07m-02]To further develop what I learned while studying abroad
○Akinobu Matsumoto(Graduate School of Science, Nagoya University)
[1S07m-03]Difference of Research Culture between Japan and the US through the angle of Systems Immunology Research
○Motohiko Kadoki1,2,3, Daniel G. Graham1,2,3, Ramnik J. Xavier1,2,3(1.Harvard Medical School, 2.Massachusetts General Hospital, 3.Broad Institute of MIT and Harvard)
[1S07m-04]The pathophysiological roles of amino acid transporter SLC7A5 in breast cancer
○Yasuhiro Saito(Institute for Advanced Biosciences, Keio University)
[1S07m-05]Immunogenetics to understand the etiology of autoimmunity
○Kazuyoshi Ishigaki1,2,3(1.Department of Microbiology and Immunology, Keio University School of Medicine, 2.Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q), 3.Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences)
[1S07m-06]Discussion
[1S08m-01]PROTACs and molecular glue protein degraders: Molecular mechanism and drug design
○Alessio Ciulli(University of Dundee)
[1S08m-02]Non-conventional PROTACs - Turning stress-response pathways into Trash-Anything machines
○Tim Clausen(Research Institute of Molecular Pathology)
[1S08m-03]Development of IAP-based PROTACs, SNIPERs
○Mikihiko Naito(The University of Tokyo)
[1S08m-04]Targeted protein degradation in mitochondria
○Minoru Ishikawa(Graduate School of Life Scineces)
[1S08m-05]Development and application of protein degrader-dependent interaction analysis method
○Satoshi Yamanaka1,2, Yuta Yanagihara3, Kohei Nishino4, Yuuki Imai3, Hidetaka Kosako4, Tatsuya Sawasaki2(1.Division of Proteo-Interactome, Proteo-Science Center, Ehime University, 2.Division of Cell-Free Sciences, Proteo-Science Center, Ehime University, 3.Division of Integrative Pathophysiology, Proteo-Science Center, Ehime University, 4.Division of Cell Signaling, Fujii Memorial Institute of Advanced Medical Sciences, Tokushima University)
[1S09m-00]Introduction
○Takafumi Suzuki(Tohoku University)
[1S09m-01]Molecular Mechanisms and Physiological Roles of the KEAP1-NRF2 Regulatory System
○Takafumi Suzuki, Masayuki Yamamoto(Tohoku University)
[1S09m-02]Discovery of CH7450924, an NRF2 Activator Targeting KEAP1-NRF2 Protein-Protein Interaction (PPI), and Its Efficacy in Preclinical Multiple Organ Dysfunction Syndrome Models
○Yukari Yasui1, Masaki Hoshino2, Shun Mistumata1, Atsushi Kimbara1, Takeo Harada1, Naoshi Horiba1(1.Research Division, Chugai Pharmaceutical Co., Ltd., 2.Chugai Research Institute for Medical Science, Inc.)
[1S09m-03]Yin-Yang regulatory dynamic of NRF1 through N-glycosylation
○Yukiko Yoshida(Tokyo Metropolitan Institute of Medical Science)
[1S09m-04]Nrf3 drives cancer immune evasion via MHC-I degradation
○Tsuyoshi Waku(Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University)
[1S09m-05]Molecular Basis of Transcriptional Regulation by Dimers Involving Small Maf Proteins
○Fumiki Katsuoka(Advanced Research Center for Innovations in Next-Generation Medicine, Tohoku Univ.)
[1S09m-06]Discussion
○Fumiki Katsuoka(Advanced Research Center for Innovations in Next-Generation Medicine, Tohoku Univ.)
[1S10m-01]Analysis of the mechanism of organelle sharing between melanocytes and keratinocytes
○Mitsunori Fukuda(Lab. of Membr. Trafficking Mech., Grad. Sch. of Life Sci., Tohoku Univ.)
[1S10m-02]Efficiency of protein transfer through the protrusion-derived extracellular vesicles
○Shiro Suetsugu(Nara Institute of Science and Technology)
[1S10m-03]Intracellular remodeling mechanisms and their physiological functions during oocyte-to-embryo transition
○Ken Sato1, Ichiro Kawasaki1, Kenta Sugiura1, Shunichi Suto1, Ikuko Maejima1, Taeko Sasaki2, Hidetaka Kosako3, Miyuki Sato2(1.Lab. of Mol. Traffic, IMCR, Gunma Univ., 2.Lab. of Mol. Membrane Biol., IMCR, Gunma Univ., 3.Div. of Cell Signaling, Insti. of Advanced Med. Sci., Tokushima Univ.)
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