[1S09m] Molecular basis of multiple physiological functions by the CNC-sMAF transcription factors

9:25 AM - 9:48 AM JST(12:25 AM - 12:48 AM UTC)

[1S09m-02] Discovery of CH7450924, an NRF2 Activator Targeting KEAP1-NRF2 Protein-Protein Interaction (PPI), and Its Efficacy in Preclinical Multiple Organ Dysfunction Syndrome Models

^○Yukari Yasui¹, Masaki Hoshino², Shun Mistumata¹, Atsushi Kimbara¹, Takeo Harada¹, Naoshi Horiba¹ (1.Research Division, Chugai Pharmaceutical Co., Ltd., 2.Chugai Research Institute for Medical Science, Inc.)

キーテクノロジー：創薬

Keywords:

KEAP1,NRF2,多臓器障害

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