[1S09m-02]Discovery of CH7450924, an NRF2 Activator Targeting KEAP1-NRF2 Protein-Protein Interaction (PPI), and Its Efficacy in Preclinical Multiple Organ Dysfunction Syndrome Models
○Yukari Yasui1, Masaki Hoshino2, Shun Mistumata1, Atsushi Kimbara1, Takeo Harada1, Naoshi Horiba1(1.Research Division, Chugai Pharmaceutical Co., Ltd., 2.Chugai Research Institute for Medical Science, Inc.)
キーテクノロジー:創薬
Keywords:
KEAP1,NRF2,多臓器障害
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