The 13th Annual Meeting of the Asian Organization for Crohn’s and Colitis（AOCC2025）
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Oral Oresentation 13

Fri. Jul 11, 2025 9:00 AM - 10:15 AM JST
Fri. Jul 11, 2025 12:00 AM - 1:15 AM UTC
Room Ⅵ(Makuhari Messe Meeting Room 105)
Chair:Mao Ren, Yoshiyuki Mishima
9:00 AM - 9:06 AM JST(12:00 AM - 12:06 AM UTC)

[O13-01]Exploring the Role of Galactose-Deficient IgA in Ulcerative Colitis: From Biomarker Potential to Cytokine-Driven Mechanisms

*Tsungyu Tsai1,2,3, Jye-Lin Hsu4,5 (1. Center for Digestive Medicine, China Medical University Hospital, Taichung, Taiwan, 2. School of Medicine, China Medical University, Taichung Taiwan, 3. Immunology Research Center, National Health Research Institutes, Zhunan, Taiwan, 4. Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, 5. Drug Development Center, China Medical University, Taichung, Taiwan)
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9:06 AM - 9:12 AM JST(12:06 AM - 12:12 AM UTC)

[O13-02]Chronic intestinal inflammation causes persistent alterations in DNA methylation and the immunological function of intestinal macrophages

*Nobuki Nemoto1, Jun Miyoshi1, Noriaki Oguri1, Haruka Wada1, Yuu Nishinarita1, Minoru Matsuura1, Tadakazu Hisamatsu1 (1. Kyorin University)
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9:12 AM - 9:18 AM JST(12:12 AM - 12:18 AM UTC)

[O13-03]The Antifibrotic Properties of Meflin in Intestinal Fibroblasts Improve Intestinal Fibrosis in Experimental Inflammatory Bowel Disease

*Jingxi Mu1, Keiko Maeda1, Masanao Nakamura1, Atsushi Enomoto2, Hiroki Kawashima1 (1. Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, 2. Department of Pathology, Nagoya University Graduate School of Medicine)
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9:18 AM - 9:24 AM JST(12:18 AM - 12:24 AM UTC)

[O13-04]Serum lipidomic profile predict disease behavior progression in treatment-naïve patients with Crohn’s disease

*Caiguang Liu1, Jinshen He1, Shixian Hu1, Ren Mao1 (1. The First Affiliated Hospital, Sun Yat-sen University)
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9:24 AM - 9:30 AM JST(12:24 AM - 12:30 AM UTC)

[O13-05]DECORIN PREVENTS INTESTINAL FIBROSIS BY SUPPRESSING ATF3 IN CROHN'S DISEASE

*Jing Nie1, Fan Hu1, Xiaomin Wu1, Zhiyin Feng1, Yao Zhang2, Longyuan Zhou1, Ren Mao1 (1. The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China., 2. Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)
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9:30 AM - 9:36 AM JST(12:30 AM - 12:36 AM UTC)

[O13-06]Usefulness of fecal eosinophil-derived neurotoxin in the treatment strategy for ulcerative colitis

*Yoshiyuki Mishima1, Shinsaku Tanaka1, Naoki Oshima1, Kousaku Kawashima1, Shunji ISHIHARA1 (1. Shiamane Unicersity, Faculty of Medicine)
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9:36 AM - 9:42 AM JST(12:36 AM - 12:42 AM UTC)

[O13-07]Genetic and Clinical Characteristics of Difficult-to-Treat Crohn's Disease: Trio-Based Exome Sequencing in 24 Families

Huibo Wu1, Zhaoyuan Xu1, Qi Zhang1, Min Zhang1, Wei Wang1, *Min Zhi1 (1. the Sixth Affiliated Hospital of Sun Yat-Sen University)
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9:42 AM - 9:48 AM JST(12:42 AM - 12:48 AM UTC)

[O13-08]Long-term dynamics in mucosal cytokine expression in patients with ulcerative colitis

*Eiki Murakami1, Haruna Horikawa1, Kazuhiko Uchiyama1, Tomohisa Takagi1 (1. Kyoto Prefectural University of Medicine)
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9:48 AM - 9:54 AM JST(12:48 AM - 12:54 AM UTC)

[O13-09]Serum Metabolomic Characteristics of Patients with Gastrointestinal Behçet's Disease and the Relationship with Prognosis

*Xiaoman Zu1,2 (1. Department of Digestive Medicine, The First Affiliated Hospital of Zhengzhou University, 2. Department of Gastroenterology, First Affiliated Hospital of Sun Yat sen University)
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9:54 AM - 10:00 AM JST(12:54 AM - 1:00 AM UTC)

[O13-10]Sarcopenia Exacerbating Colitis via Modulation of the Colonic S100A9/TLR4 Inflammatory Axis

*Yong Li1, Duo Xu1, Shengdi Zhang1, Yu Peng1, Xiaowei Liu1 (1. Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China)
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10:00 AM - 10:06 AM JST(1:00 AM - 1:06 AM UTC)

[O13-11]Treatment of Patient-Derived Colonic Organoids with Urolithin A Reveals Transcriptomic Remodeling of the Intestinal Stem Cell Niche in Ulcerative Colitis: Establishment of a Novel Platform

*Aditya Bajaj1, Manasvini Markandey1, Mukesh Singh1, Mahak Verma1, Shubham Prasad1, Himanshu Narang1, David Mathew1, Saurabh Kedia1, Vineet Ahuja1 (1. Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India)
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10:06 AM - 10:12 AM JST(1:06 AM - 1:12 AM UTC)

[O13-12]Serum proteomic and metabonomic profile predict early remission to anti-integrin therapy in patients with moderate to severe ulcerative colitis

*Yinghao Sun1, Hong Yang1 (1. Peking Union Medical College Hospital)
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10:12 AM - 10:15 AM JST(1:12 AM - 1:15 AM UTC)

[26001-12-13add]Oral Presentaion

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