The 13th Annual Meeting of the Asian Organization for Crohn’s and Colitis（AOCC2025）
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Oral PresentationOral Presentaion

Oral Oresentation 14

Fri. Jul 11, 2025 10:30 AM - 11:45 AM JST
Fri. Jul 11, 2025 1:30 AM - 2:45 AM UTC
Room Ⅵ(Makuhari Messe Meeting Room 105)
Chair:Kazuhiko Uchiyama, Yohei Mikami
10:30 AM - 10:36 AM JST(1:30 AM - 1:36 AM UTC)

[O14-01]Oral highly-virulent pathogenic isolates aggravated colitis through gut microbiota-equol-ERβ axis

*Jingyi Chen1, Congyi Yang1, Yalan Xu1, Yuzheng Zhao1, Jushan Wu1, Yulan Liu1, Ning Chen1 (1. Department of Gastroenterology, Peking University People's Hospital)
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10:36 AM - 10:42 AM JST(1:36 AM - 1:42 AM UTC)

[O14-02]Effects of Different Sized Microplastic Exposure on Gut Microbiota and Inflammatory Responses Ulcerative Colitis

*Yan Zhang1, Xiaohan Wan1, Yanqing Li1 (1. Qilu Hospital of Shandong University)
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10:42 AM - 10:48 AM JST(1:42 AM - 1:48 AM UTC)

[O14-03]Gut Bacteria Prevotellaceae Related Lithocholic Acid Metabolism Promotes Colonic Inflammation

Liping Chen1, *Fang Xiao1 (1. Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P. R. China)
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10:48 AM - 10:54 AM JST(1:48 AM - 1:54 AM UTC)

[O14-04]Butyrate-producing D.welbionis modulates neutrophil function to inhibit intestinal inflammation through the HDACi pathway

*Yingying Cao1, Yan Shi2, Xinjian Wan2 (1. Department of Gastroenterology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 2. Digestive Endoscopic Center, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine)
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10:54 AM - 11:00 AM JST(1:54 AM - 2:00 AM UTC)

[O14-05]Shared and Distinct Features of the Gut Microbiome Signatures in Immune-mediated Inflammatory Diseases: Initial Findings from the INTEGRATE Cohort Study

*Shin Ju Oh1, Hyun Sik Kim2, Bora Nam3, Jae-Yun Lee4, Ji Eun Kim1, Bo-Hyung Kim5, Tae-woo Kim6, Soo-Kyung Park6, Sang Woon Lee7, Yeon-Ah Lee8, Dong-Il Park6, Tae-Hwan Kim3, Chang Kyun Lee1 (1. Department of Gastroenterology, Center for Crohn's and Colitis, Kyung Hee University Hospital, Kyung Hee University College of Medicine, Seoul, Republic of Korea, 2. Department of Biology, Kyung Hee University, Seoul, Republic of Korea, 3. Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, 4. Department of Life and Nanopharmaceutical Science, Kyung Hee University, Seoul, Republic of Korea, 5. Department of Clinical Pharmacology and Therapeutics, Kyung Hee University Medical Center, Seoul, Republic of Korea, 6. Division of Gastroenterology, Department of Internal Medicine and Inflammatory Bowel Disease Center, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul, Republic of Korea, 7. Department of Clinical Pharmacology and Therapeutics, Hanyang University Seoul Hospital, Seoul, Republic of Korea, 8. Division of Rheumatology, Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Republic of Korea)
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11:00 AM - 11:06 AM JST(2:00 AM - 2:06 AM UTC)

[O14-06]IL4I1 regulates macrophage senescence and gut microbiota homeostasis in IBD

*Ai Li1, Zhongsheng Feng1, Jinghan Hua1, Zhanju Liu1 (1. Center for IBD Research and Department of Gastroenterology, Shanghai Tenth People's Hospital of Tongji University)
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11:06 AM - 11:12 AM JST(2:06 AM - 2:12 AM UTC)

[O14-07]Kushenol A modulates gut microbiota and repairs mucin sulfation modification disorder to alleviate ulcerative colitis

*Hongsuo CHEN1,2, Hailong Cao1, zhenyu Jiang2 (1. Tianjin Medical University General Hospital, 2. The Second Afffliated Hospital of Baotou Medical College)
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11:12 AM - 11:18 AM JST(2:12 AM - 2:18 AM UTC)

[O14-08]Microbiota-induced S100B-RAGE axis mediates enteric glia-macrophage crosstalk and promotes colitis

*Mengfan Li1, Hailong Cao1 (1. Tianjin Medical University General Hospital)
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11:18 AM - 11:24 AM JST(2:18 AM - 2:24 AM UTC)

[O14-09]Christensenella minuta is trained by cholic acid to ameliorates colitis by modulating gut metabolism

*Linxiang Zhou1, Jintao Xiao1, Xingyang Luo1, Haiyue He1, Xiaowei Liu1 (1. Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, China)
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11:24 AM - 11:30 AM JST(2:24 AM - 2:30 AM UTC)

[O14-10]Early-Life Microbial Deprivation Impairs the Ontogeny of Intestinal tissue resident memory T cells and Exacerbates Ulcerative Colitis Pathogenesis

*Yaqian Yang1, Peiling Huang1, Yani yin1, Xiaowei Liu1,2 (1. Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China, 2. National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China)
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11:30 AM - 11:36 AM JST(2:30 AM - 2:36 AM UTC)

[O14-11]Salivary Exosomal SAA1/2 Drive Gut Inflammation via the Oral-Gut Axis in Active IBD

*Congyi Yang1, Jingyi Chen1, Ning Chen1,2 (1. Department of Gastroenterology, Peking University People’s Hospital, 2. Clinical Center of Immune-Mediated Digestive Diseases, Peking University People’s Hospital)
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11:36 AM - 11:42 AM JST(2:36 AM - 2:42 AM UTC)

[O14-12]Protective effects of Lacticaseibacillus rhamnosus GG on gut inflammation in zebrafish

*Yang Yang1, Fang Yan2,3 (1. Department of Gastroenterology, Sir Run Run Hospital, Nanjing Medical University, 2. Geriatric Diseases Institute of Chengdu, Department of Geriatrics, Chengdu Fifth People’s Hospital (Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine), 3. Center for Medicine Research and Translation, Chengdu Fifth People’s Hospital (Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine))
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11:42 AM - 11:45 AM JST(2:42 AM - 2:45 AM UTC)

[26013-24-13add]Oral Presentaion

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