The 13th Annual Meeting of the Asian Organization for Crohn’s and Colitis（AOCC2025）
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Poster Oral PresentationPoster Oral Presentaion

Poster Oral Presentation 12

Fri. Jul 11, 2025 1:00 PM - 1:45 PM JST
Fri. Jul 11, 2025 4:00 AM - 4:45 AM UTC
Room Ⅶ (Makuhari Messe International Conference Room)(Makuhari Messe International Conference Room) 12

[PO-112]Susceptibility gene MFSD12-variant drives intestinal inflammation via mTORC1-ATOH8-SFRP1 axis in CD4+ T cells

*Jian Lin1,2, Long Ju1, Zhanju Liu1 (1. Center for IBD Research and Department of Gastroenterology, Shanghai Tenth People’s Hospital of Tongji University, 2. Department of Gastroenterology, Affiliated Hospital of Putian University)
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[PO-113]The susceptibility gene MFSD12 variation exacerbates colitis through SPRAC-mediated macrophage repolarization

*Jian Lin1,2, Zhongsheng Feng1, Zhanju Liu1 (1. Center for IBD Research and Department of Gastroenterology, Shanghai Tenth People’s Hospital of Tongji University, 2. Department of Gastroenterology, Affiliated Hospital of Putian University)
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[PO-114]Systemic Deletion of DUOX2 Protect Mice from DSS-induced Intestinal Inflammation

*Yalan Xu1,2, Congyi Yang1,2, Jingyi Chen1,2, Yuzheng Zhao1,2, Ning Chen1,2 (1. Peking University, 2. Peking University People's Hospital)
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[PO-115]Epithelial MST1 deficiency promotes pyroptosis and aggravates inflammatory bowel disease via the YAP/p73 signaling pathway

*Jiali Lu1, Mei Ye1 (1. Zhongnan Hosp., Wuhan Univ.)
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[PO-116]L-Type Amino Acid Transporter 1 Plays a Key Role in Tissue Repair in DSS-Induced Colitis

*Norihiro Okamoto1, Yunlong Sui1,4, Namiko Hoshi2,1, Misaki Agawa1, Hirotaka Nakamura1, Yuki Ito1, Haruka Miyazaki1, Yuna Ku1, Daisuke Watanabe1, Makoto Ooi3,1, Hui Yang4, Yuzo Kodama1 (1. Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 2. Division of Integrated Analyses of Bioresource and Health Care, Kobe University Graduate School of Medicine, 3. Department of Gastroenterology, Kobe University International Clinical Cancer Research Center, 4. Department of Gastroenterology, The Second Affiliated Hospital of Guangzhou Medical University)
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[PO-117]Piezo1-Mediated Lactate Metabolism via HIF-1α-MCT1 Axis Exacerbates Intestinal Inflammation in IBD

*Chang Liang1, Yuan Xia1, Yan Zhang1 (1. Department of Gastroenterology, West China Hospital of Sichuan University)
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[PO-118]Inhibition of CIRP Nuclear Export Modulates the mtDNA-Driven PANoptosis Axis to Attenuate Colonic Mucosal Damage in Ulcerative Colitis

*Yuzhu Di1, Hui Li1, Yuxin Zhu1, Lubo Jin1, Le Kang2, Bo Qu1 (1. The Second Affiliated Hospital of Harbin Medical University, Heilongjiang Province, China , 2. Department of Endoscopy, Fudan University Shanghai Cancer Center, Shanghai, China)
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[PO-119]Research on the Expression of Phosphodiesterase 4B in Inflammatory Bowel Disease and Its Mechanism of Regulating Intestinal Inflammation

*Jingyi Ju1, Meng Sun1, Mengqi Luo1, Zhaoyang Li1, Yufang Wang1 (1. Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, China)
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[PO-120]S-equol, a metabolite of dietary soy isoflavones, alleviates DSS-induced colitis in mice through binding to ERβ

*Jingyi Chen1, Congyi Yang1, Yalan Xu1, Yuzheng Zhao1, Jushan Wu1, Yulan Liu1, Ning Chen1 (1. Department of Gastroenterology, Peking University People's Hospital)
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[PO-121]Exploring the Effects and Mechanisms of Sanren Tang in Ulcerative Colitis Mice via Modulation of the B-Cell Receptor Signaling Pathway

Guo DongLiang1, Li Tianyi1, Ge Yuanyuan1, *Ding Kang1 (1. Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine)
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[PO-122]Kushenol A reprograms PPARγ signaling-mediated lipid metabolism of macrophages to attenuate colitis

*Xin Wang1, Hailong Cao1 (1. Tianjin Medical University General Hospital)
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