Session Details
Poster Oral Presentation 2
Fri. Jul 11, 2025 1:00 PM - 1:45 PM JST
Fri. Jul 11, 2025 4:00 AM - 4:45 AM UTC
Fri. Jul 11, 2025 4:00 AM - 4:45 AM UTC
Room Ⅶ (Makuhari Messe International Conference Room)(Makuhari Messe International Conference Room) 2
[PO-012]Etrasimod efficacy in patients with mildly to moderately active ulcerative colitis (modified Mayo score 4–6) in the phase 3 ELEVATE UC clinical program
Dana Verbovsky, Andres J Yarur1, Geert R D'Haens2, Filip Baert3, Martina Goetsch4, Chuanbo Zang5, Guibao Gu6, Rafal Mazur4, Michael Keating7, Elizabeth Kudlacz8, Sarah Sidhu7, *Karolina Wosik9, Silvio Danese10 (1. Inflammatory Bowel Disease Center and Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA, 2. Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam, The Netherlands, 3. Department of Gastroenterology, AZ Delta, Roeselare, Belgium, 4. Pfizer AG, Zürich, Switzerland, 5. Pfizer Inc, Collegeville, PA, USA, 6. Pfizer Inc, La Jolla, CA, USA, 7. Pfizer Inc, New York, NY, USA, 8. Pfizer Inc, Groton, CT, USA, 9. Pfizer Canada, Kirkland, QC, Canada, 10. Division of Gastroenterology and Endoscopy, IRCCS San Raffaele Hospital and Vita Salute San Raffaele University, Milan, Italy)
[PO-013]Etrasimod for the treatment of ulcerative colitis: up to 4 years of safety data from the global clinical program
Dana Verbovsky, Séverine Vermeire1, David T Rubin2, Miguel D Regueiro3, *Ken Takeuchi4, Alissa Walsh5, Paulo G Kotze6, Aline Charabaty7, Martina Goetsch8, Krisztina Lazin8, Joseph Wu9, Georgios Tsamos10, Michelle Segovia11, Diogo Branquinho11, Silvio Danese12 (1. Department of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium, 2. University of Chicago Medicine Inflammatory Bowel Disease Center, Chicago, IL, USA, 3. Department of Gastroenterology, Hepatology and Nutrition, Cleveland Clinic, Cleveland, OH, USA, 4. Department of Gastroenterology, IBD Centre, Tsujinaka Hospital Kashiwanoha, Kashiwa, Chiba, Japan, 5. Translational Gastroenterology Unit, Oxford University Hospital, Oxford, UK, 6. IBD Outpatient Clinics, Colorectal Surgery Unit, Pontifícia Universidade Católica do Paraná (PUCPR), Curitiba, Brazil, 7. Division of Gastroenterology and Hepatology, Johns Hopkins School of Medicine, Washington, DC, USA, 8. Pfizer AG, Zürich, Switzerland, 9. Pfizer Inc, Cambridge, MA, USA, 10. Pfizer, Thessaloniki, Central Macedonia, Greece, 11. Pfizer Inc, New York, NY, USA, 12. Division of Gastroenterology and Endoscopy, IRCCS San Raffaele Hospital and Vita Salute San Raffaele University, Milan, Italy)
[PO-014]Pregnancy outcomes in the etrasimod clinical program
Dana Verbovsky, Krisztina B Gecse1, María Chaparro2, Maria T Abreu3, Yvette Leung4, Elena Sonnenberg5, Aoibhinn McDonnell6, Krisztina Lazin7, Joseph Wu8, Christina C Smith9, Márjori Dulcine10, *Karolina Wosik11 (1. Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands, 2. Department of Gastroenterology, Hospital Universitario de La Princesa, IIS Princesa, UAM, CIBERehd, Madrid, Spain, 3. F. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai, Los Angeles, CA, USA, 4. Department of Medicine, University of British Columbia, Vancouver, BC, Canada, 5. Medizinische Klinik m. S. Gastroenterologie, Infektiologie und Rheumatologie, Charité-Universitätsmedizin Berlin, Berlin, Germany, 6. Pfizer Ltd, Sandwich, UK, 7. Pfizer AG, Zürich, Switzerland, 8. Pfizer Inc, Cambridge, MA, USA, 9. Pfizer Inc, Collegeville, PA, USA, 10. Pfizer Brazil, São Paulo, Brazil, 11. Pfizer Canada, Kirkland, QC, Canada)
[PO-015]The impact of etrasimod on the transcriptome in colon biopsies using RNA-seq: data from ELEVATE UC 52 and ELEVATE UC 12 phase 3 clinical trials
Dana Verbovsky, Britta Siegmund1,2, Rathi D Ryan3, Catherine M Crosby4, Maria T Abreu5, Séverine Vermeire6, Iris Dotan7,8, Keren M Rabinowitz7,9, Xiang Guo10, H Kiyomi Komori11, Martina Goetsch12, *Karolina Wosik13, John C Woolcott10, Silvio Danese14 (1. Med. Klinik für Gastroenterologie, Infektiologie, Rheumatologie, Charité – Universitätsmedizin Berlin, Berlin, Germany, 2. Freie Universität Berlin, Humboldt-Universität zu Berlin, Campus Benjamin Franklin, Berlin, Germany, 3. Pfizer Inc, San Francisco, CA, USA, 4. Pfizer Inc, La Jolla, San Diego, CA, USA, 5. F. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai, Los Angeles, CA, USA, 6. Department of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium, 7. Division of Gastroenterology, Rabin Medical Center, Petah Tikva, Israel, 8. Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel, 9. Felsentstein Medical Research Centre, Medical and Health Sciences, Tel Aviv, Israel, 10. Pfizer Inc, Collegeville, PA, USA, 11. Formerly Arena Pharmaceuticals, San Diego, CA, USA; a wholly-owned subsidiary of Pfizer Inc, New York, NY, USA, 12. Pfizer AG, Zürich, Switzerland, 13. Pfizer Canada, Kirkland, QC, Canada, 14. Division of Gastroenterology and Endoscopy, IRCCS San Raffaele Hospital and Vita Salute San Raffaele University, Milan, Italy)
[PO-016]Integrated Long-Term Safety of Ozanimod From Clinical Trials Across 2 Different Indications
*Hiroshi Nakase1, David T. Rubin2, Silvio Danese3, Peter Irving4, Douglas C. Wolf5, Preetika Sinh6, Bruce A. C. Cree7, Olga Alekseeva8, Fred D. Lublin9, Norma Ruiz Santiago10, Zhaohui Liu10, AnnKatrin Petersen10, Dimpy Mehra10, Anjali Jain10, Anthony Krakovich10, Chun-Yen Cheng10, Jon V. Riolo10, Erik DeBoer10, Jeffrey A. Cohen11, Ryan C. Ungaro9 (1. Sapporo Medical University, Sapporo, Japan, 2. University of Chicago Medicine, Inflammatory Bowel Disease Center, Chicago, IL, USA, 3. Department of Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele and University Vita-Salute San Raffaele, Milan, Italy, 4. Guy’s and St Thomas’ NHS Foundation Trust, London, UK, 5. Center for Crohn’s Disease & Ulcerative Colitis, Atlanta Gastroenterology Associates, Atlanta, GA, USA, 6. Division of Gastroenterology, Medical College of Wisconsin, Milwaukee, WI, USA, 7. Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA, USA, 8. Department of Gastroenterology, Nizhny Novgorod Regional Clinical Hospital, Nizhny Novgorod, Russia, 9. Icahn School of Medicine at Mount Sinai, New York, NY, USA, 10. Bristol Myers Squibb, Princeton, NJ, USA, 11. Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic, Cleveland, OH, USA)
[PO-017]Safety of Long-Term Ozanimod Treatment Up to 5 Years in Patients With Moderately to Severely Active Ulcerative Colitis: An Interim Analysis of the True North Open-Label Extension
*Taku Kobayashi1, Joana Torres2, Randy Longman3, Konstantinos Katsanos4, Scott Lee5, Dominik Bettenworth6, Louis Korman7, Dimpy Mehra8, Norma Ruiz Santiago8, AnnKatrin Petersen8, Manik Desai8, Hsiuanlin Wu8, Dong Wang9, Mark T. Osterman8, Anjali Jain8, Bincy P. Abraham10 (1. Kitasato University Kitasato Institute Hospital, Tokyo, Japan, 2. Division of Gastroenterology, Hospital da Luz and Hospital Beatriz Angelo, Lisbon, Portugal; and Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal, 3. Weill Cornell Medicine, New York, NY, USA, 4. Division of Gastroenterology, University of Ioannina, Ioannina, Greece, 5. Digestive Health Center, University of Washington Medical Center, Seattle, WA, USA, 6. University of Münster, Münster, Germany; and CED Schwerpunktpraxis, Münster, Germany, 7. Capital Digestive Care, Washington, DC, USA, 8. Bristol Myers Squibb, Princeton, NJ, USA, 9. Bristol Myers Squibb K. K., Tokyo, Japan, 10. Houston Methodist-Weill Cornell, Houston, TX, USA)
[PO-018]Sustained Efficacy and Safety After 5 Years of Continuous Ozanimod Treatment Independent of Clinical Remission Status: An Interim Analysis of the True North Open-Label Extension Study
*Silvio Danese1, Raymond K. Cross2, Douglas C. Wolf3, Katsuyoshi Matsuoka4, Iris Dotan5, Brigid S. Boland6, Laura E. Raffals7, Dimpy Mehra8, Norma Ruiz Santiago8, AnnKatrin Petersen8, Manik Desai8, Hsiuanlin Wu8, Dong Wang9, Mark T. Osterman8, Anjali Jain8, James O. Lindsay10 (1. Department of Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele and University Vita-Salute San Raffaele, Milan, Italy, 2. Melissa L. Posner Institute for Digestive Health & Liver Disease at Mercy Medical Center, Baltimore, MD, USA, 3. Center for Crohn’s Disease & Ulcerative Colitis, Atlanta Gastroenterology Associates, Atlanta, GA, USA, 4. Toho University Sakura Medical Center, Sakura, Chiba, Japan, 5. The Division of Gastroenterology, Rabin Medical Center, Petah Tikva, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel, 6. Department of Medicine, University of California San Diego, La Jolla, CA, USA, 7. Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA, 8. Bristol Myers Squibb, Princeton, NJ, USA, 9. Bristol Myers Squibb K. K., Tokyo, Japan, 10. Barts and the London School of Medicine and Dentistry, London, UK)
[PO-019]Efficacy of Ozanimod in Patients With Moderately to Severely Active Ulcerative Colitis With Prior Use of 5-Aminosalicylic Acid Only: A Pooled Analysis of True North and J-True North
*TADAKAZU HISAMATSU1, Hiroshi Nakase2, Katsuyoshi Matsuoka3, Masayuki Saruta4, Taku Kobayashi5, Takahiro Katayama6, Kazuhiro Toriyama6, Dong Wang6, Yoko Uchikawa6, Anjali Jain7, Angela Ren7, Toshifumi Hibi5 (1. Kyorin University School of Medicine, Tokyo, Japan, 2. Sapporo Medical University, Sapporo, Japan, 3. Toho University Sakura Medical Center, Chiba, Japan, 4. Jikei Medical University, Tokyo, Japan, 5. Kitasato University Kitasato Institute Hospital, Tokyo, Japan, 6. Bristol Myers Squibb K. K., Tokyo, Japan, 7. Bristol Myers Squibb, Princeton, NJ, USA)
[PO-020]Efficacy and Safety of Risankizumab Among Patients in East Asia With Ulcerative Colitis: A Post Hoc Subanalysis of the Randomized Phase 2b/3 INSPIRE and Phase 3 COMMAND Studies
*Tadakazu Hisamatsu1, Ken Takeuchi2, Qian Cao3, Keiji Ozeki4, Sang-Bum Kang5, Jen-Wei Chou6, Madhuja Mallick7, Tomoko Matsuda8, Pierre A Morisset7, Jasmina Kalabic9, Yuji Ogawa8, Yafei Zhang7, Yuh-Ying Yeh7 (1. Department of Gastroenterology and Hepatology, Kyorin University School of Medicine, 2. Department of Gastroenterology, IBD Centre, Tsujinaka Hospital Kashiwanoha, 3. Department of Gastroenterology and Inflammatory Bowel Disease Center, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 4. Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, 5. Department of Internal Medicine, Daejeon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, 6. Center for Digestive Disease, Department of Internal Medicine, China Medical University Hospital, 7. AbbVie Inc., 8. AbbVie GK, 9. AbbVie Deutschland GmbH & Co. KG)
[PO-021]Efficacy of risankizumab in patients with UST-experienced Crohn's disease.
*Shinji Ota1, Taka Asari1, Yohei Sawada1, Kyoko Amenomori1, Tetsuya Tatsuta1, Keisuke Hasui1, Hidezumi Kikuchi1, Hiroto Hiraga1, Daisuke Chinda1, Hirotake Sakuraba1 (1. Department of Gastroenterology, Hematology and Clinical immunology, Hirosaki University Graduate School of Medicine)
[PO-022]Unveiling the Power of Ustekinumab: A Promising Therapy for Crohn's Disease Patients with Symptomatic Intestinal Strictures
*Jingwen Liu1, Wen Hu2, Shuyan Li1, Shurong Hu1, Yan Chen1 (1. the Second Affiliated Hospital of Zhejiang University School of Medicine, 2. the First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine))