Odd (2P-001~2P-047)

[2P-003] Structural study of a novel carbazole prenyltransferase that resembles squalene synthase

*Hironori Suemune¹, Ryuhei Nagata^2,3, Masaya Kobayashi², Tetsuro Shinada⁴, Makoto Nishiyama^5,6, Tomohisa Kuzuyama^2,6, Yusuke Sato¹, Tomoya Hino¹, Shingo Nagano¹ (1. Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, 2. GSALS, UTokyo, 3. JSPS Research Fellow PD, 4. Faculty of Science, Osaka City University, 5. BRC, UTokyo, 6. CRIIM, UTokyo)

Keywords:

X-ray crystal structure analysis

スクアレン合成酵素に類似した放線菌由来の新規カルバゾールプレニル基転移酵素の反応メカニズム解明を目指し、CqsB4, LvqB4二つの酵素のX線結晶構造解析を行なった。