The 16th Symposium on Biorelevant Chemistry
Sep 10 - Sep 12, 2022Held On-site and Online
The 16th Symposium on Biorelevant Chemistry
Sep 10 - Sep 12, 2022Held On-site and Online
[1A-08]CRISPR/Cas12-Based Sensor Array for the Multiplex DNA detection
*Hiroki Shigemori1,2, Satoshi Fujita1, Eiichi Tamiya1,3, Shin-ichi Wakida1, Hidenori Nagai1,2(1. Advanced Photonics and Biosensing Open Innovation Laboratory, AIST-Osaka Unverisity, 2. Graduate School of Human Development and Environment, Kobe University, 3. The Institute of Scientific and Industrial Research, Osaka University)
Keywords:
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR),Nucleic acid detection,Multiplex sensor array,Nuclease,Mutation analysis
CRISPR/Cas12 systems have excellent recognition ability for nucleic acid sequence, that can be utilized for biosensors. Herein, we developed a CRISPR/Cas12-based sensor array for the one-pot multiplex DNA detection