The 18th Symposium on Biorelevant Chemistry

Presentation Information

5:20 PM - 5:40 PM JST(8:20 AM - 8:40 AM UTC)

[1OA-14]Identification of a Kinetically HDAC2-selective Inhibitor and its Pharmacological Effects

*Yukihiro Itoh^1,2, Toshifumi Tojo², Takashi Kurohara^1,2, Ying Li², Ritesh Singh², Remy Narozny¹, van der Wiel Alexander², Yuka Miyake^1,2, Yasunobu Yamashita¹, Shusaku Uchida^3,4, Takayoshi Suzuki^1,2 (1. SANKEN, Osaka University, 2. Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 3. Medinal Innovation Center, Kyoto University, 4. Nagoya City University Graduate School of Medical Sciences))

Keywords:

Enzyme inhibition kinetics,Histone deactylase,dissociation rate constant

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