Presentation Information
[1OB-05]Development of Chemically Modified mRNA based on Chemical Synthesis for Highly Efficacious mRNA Therapeutics
*Yasuaki Kimura1, Hiroto Iwai2, Masakazu Honma2, Hiroki Yamada2, Kosuke Nakamoto1, Masahito Inagaki1, Fumitaka Hashiya1, Naoko Abe1, Junichiro Yamamoto2, Hiroshi Abe1,3 (1. Graduate School of Science, Nagoya Univeristy, 2. Kyowa Kirin Co., Ltd., 3. Institute for Glyco-core Research)
Keywords:
mRNA,chemical synthesis,chemical modification,translational activity,stability