Presentation Information
[1P-74]Regulation of RNA cleavage by β-galactosidase-responsive cyclic antisense oligonucleotides: topological switch-off and enzyme-triggered switch-on
*Kento Miyaji1, Kohji Seio1 (1. Department of Life Science and Technology, Institute of Science Tokyo)
Keywords:
Antisense oligonucleotide,Click chemistry,Duplex stability,RNase H-mediated RNA cleavage,β-galactosidase