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Sub-molecular-scale observation of Structural Maintenance of Chromosomes complexes by high-speed AFM

High-speed AFM has been a unique experimental method that can observe single biomolecular structural dynamics at near physiological condition. However, AFM data directly provide information of the surface envelope of the specimen at intermediate resolution both in time and space so that the underlying three-dimensional structures and their movements need to be inferred from some computations for quantitative analysis. The workshop focuses on recent efforts towards integration of high-speed AFM measurements and information technology (IT)-based methods that are expected to make high-speed AFM methods more powerful in the coming years.

Biophysical Society of Japan

The 61st Annual Meeting of the Biophysical Society of Japan

The 61st Annual Meeting of the Biophysical Society of Japan

[1SEA-6]Sub-molecular-scale observation of Structural Maintenance of Chromosomes complexes by high-speed AFM