[H936-4pm] 17. Biofunctional Chemistry, Biotechnology

1:20 PM - 1:40 PM JST(4:20 AM - 4:40 AM UTC)English

[H936-4pm-02] Elucidation of the association character and 3D domain-swapped structure of a tetramerizing antibody light chain

○Takahiro Sakai¹, Shohei Yamaguchi¹, Tsuyoshi Mashima¹, Naoya Kobayash¹, Lian Duan², Ryo Fujiki², Hengphasatporn Kowit², Yasuteru Shigeta², Hideaki Ogata³, Emi Hifumi⁴, Taizo Uda⁵, Shun Hirota¹ (1. Grad. Sch. Sci. Tech., NAIST, 2. Cent. Comp. Sci., Univ. Tsukuba, 3. Grad. Sch. Sci., Univ. Hyogo, 4. Inst. Res. Mgmt., Oita Univ, 5. Nano-tech Lab., ISIT)

Keywords:

protein aggregation,antibody light chain,X-ray crystallography,thermodynamic parameters,domain swapping