Session Details
[H932-4am]17. Biofunctional Chemistry, Biotechnology
Thu. Mar 21, 2024 9:30 AM - 11:40 AM JST
Thu. Mar 21, 2024 12:30 AM - 2:40 AM UTC
Thu. Mar 21, 2024 12:30 AM - 2:40 AM UTC
H932(932, Bldg. 9 [3F])
Chair: Kazumitsu Onizuka, Takanori Oyoshi
[H932-4am-01]Synthesis of G4-PROTAC ligand for degradation of G-quadruplex binding proteins
○Yuma Tanaya1, Rena Nohara1, Ma Yue2, Kazuo Nagasawa1, Masayuki Tera1 (1. Tokyo University of Agriculture and Technology, 2. Research Core, Institute of Research, Tokyo Medical and Dental University)
[H932-4am-02]Degradation of intracellular G-quadruplex binding proteins by G4-PROTAC ligands
○Rena Nohara1, Yuuma Tanaya1, Yue Ma2, Kazuo Nagasawa1, Masayuki Tera1 (1. Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2. Research Core, Institute of Research, Tokyo Medical and Dental University)
[H932-4am-03]Selective photo-crosslinking of G-quadruplexes by a dual-recognition ligand
○Sayuri Shimada1, Ryo Ishikawa1, Kazuki Yanagida1, Yue Ma2, Shogo Sasaki1, Kazuo Nagasawa1, Masayuki Tera1 (1. Tokyo University of Agriculture and Technology, 2. Research Core, Institute of Research, Tokyo Medical and Dental University)
[H932-4am-04]Evaluation of chemical reactions in droplets with macrocyclic hexaoxazole-type G-quadruplex ligands
○Akari Oyama1, Shogo Sasaki1, Masayuki Tera1, Kazuo Nagasawa1 (1. Tokyo University of Agriculture and Technology)
[H932-4am-05]Synthetic studies of the selective G4 ligands using click chemistry
○Yuri Shimasawa1, Shogo Sasaki1, Yue Ma2, Masayuki Tera1, Kazuo Nagasawa1 (1. Tokyo University of Agriculture and Technology, 2. Research Core, Tokyo Medical and Dental University)
[H932-4am-06]Synthesis of light-up type fluorescent ligands for topology selective and dynamic detection of G-quadruplexes
○Haruki Fujita1, Naruyuki Watatani1, Syogo Sasaki1, Yue Ma2, Masayuki Tera1, Kazuo Nagasawa1 (1. Tokyo University of Agriculture and Technology, 2. Research Core, Institute of Research, Tokyo Medical and Dental University)
Break
[H932-4am-07]Novel macrocyclic pyridone pentamers as G-quadruplex (G4) ligands
○Emina Isobe1, Takayoshi Arai1, Keisuke Iida1 (1. Chiba University)
[H932-4am-08]Photo-decomposition Mechanism of Quadruplex DNA Using Anionic Phthalocyanines
○Atsuya Momotake1, Yusuke Odahara1, Yasuhiko Yamamoto1 (1. Univ. of Tsukuba)
[H932-4am-09]Investigation of pull-down unit position for large-scale analysis of RNA alkylation
○Ping-Yun Lan1,2, Kazumitsu Onizuka1,2, Yutong Chen1,2, Emi Miyashita3, Kaoru R. Komatsu3, Hirohide Saito3, Fumi Nagatsugi1,2 (1. Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2. Department of Chemistry, Graduate School of Science, Tohoku University, 3. CiRA, Kyoto University)
[H932-4am-10]Synthesis and evaluation of a turn-on fluorescent probe targeting UGGAA repeats
○Shoei Harada1, Tomonori Shibata1, Kazuhiko Nakatani1 (1. Osaka Univ., SANKEN)
[H932-4am-11]Analysis of G-quadruplex Binding Protein if EWS for Transcriptional Regulation of TERRA
○Wakana Matsudaira1, Luthfi Lulul Ulum2, Akinori Ishihara1, Takanori Oyoshi1,2,3 (1. Graduate School of integrated Science and Technology, Shizuoka University., 2. Graduate School of Science and Technology, Shizuoka University., 3. Research Institute of Green Science and Technology, Shizuoka University.)
[H932-4am-12]Development of the functional G4 DNA binding protein regulating transcription
○Natsuki Shibata1, Maiko Yamanashi2, Luthfi Lulul Ulum3, Akinori Ishihara2, Takanori Oyoshi2,3,4 (1. Faculty of Science Shizuoka University, 2. Graduate School of Integrated Science and Technology, Shizuoka University, 3. Graduate School of Science and Technology, Shizuoka University, 4. Research Institute of Green Science and Technology, Shizuoka University)