Presentation Information
[OE9-3]Impact of measuring heteroplasmy of causative mitochondrial DNA variants at the single-cell level in patients with MELAS
○Atsuko Okazaki1, Kazuhiro Nitta1,2, Yukiko Yatsuka1, Ayumu Sugiura1, Masato Arao3, Masaru Shimura4, Tomohiro Ebihara4, Takanori Onuki4, Keiko Ichimoto4, Akira Ohtake3,5,6, Kei Murayama4, Yasushi Okazaki1,2 (1.Diagnostics and Therapeutics of Intractable Diseases, Juntendo University, Graduate School of Medicine, 2.Laboratory for Comprehensive Genomic Analysis, Center for Integrative Medical Sciences, RIKEN, 3.Department of Pediatrics, Saitama Medical University, 4.Department of Metabolism, Chiba Children's Hospital, 5.Center for Intractable Diseases, Saitama Medical University Hospital, 6.Department of Clinical Genomics, Saitama Medical University)