Session Details

[OE7]Oral English Session 7 GWAS / Population Genetics

Sat. Dec 17, 2022 2:10 PM - 3:00 PM JST
Sat. Dec 17, 2022 5:10 AM - 6:00 AM UTC
Room 7
Chairs:Katsushi Tokunaga (Genome Medical Science Project, National Center for Global Health and Medicine, Tokyo, Japan), Atsushi Tajima (Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University)

[OE7-1]East Asian-specific and cross-ancestry genome-wide meta-analyses provide new insights into peptic ulcer disease genetics

Yunye He1, Masaru Koido1, Yoichi Sutoh2, Mingyang Shi1, Yayoi Yamasaki2, Takayuki Morisaki3, Akiko Nagai3, Yoshinori Murakami3, Chizu Tanikawa1, Tsuyoshi Hachiya2, Koichi Matsuda1,3, Atsushi Shimizu2, Yoichiro Kamatani1 (1.Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan, 2.Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan, 3.Institute of Medical Science, The University of Tokyo, Tokyo, Japan)

[OE7-2]The Largest Asian GWAS for Systemic Sclerosis Identified a Novel Risk Causal SNP in the Fc gamma Receptor Gene Region

Yuki Ishikawa1, Nao Tanaka1, Yoshihide Asano2,3 Masanari Kodera4, Yuichiro Shirai5, Mitsuteru Akahoshi6,7, Minoru Hasegawa8, Takashi Matsushita9, Kazuyoshi Saito10, Sei-Ichiro Motegi 11, Hajime Yoshifuji12, Ayumi Yoshizaki3, Tomohiro Komoto13, Kae Takagi14, Akira Oka15, Miho Kanda4, Yoshihito Tanaka4, Yumi Ito4, Kazuhisa Nakano10, Hiroshi Kasamatsu18, Akira Utsunomiya18, Akiko Sekiguchi11, Hiroaki Niro 6, Masatoshi Jinnin19, Katsunari Makino20, Takamitsu Makino20, Hironobu Ihn20, Motohisa Yamamoto 21, Chisako Suzuki22, Hiroki Takahashi22, Emi Nishida23,24, Akimichi Morita23, Toshiyuki Yamamoto25, Toshiyuki Yamamoto26, Yuya Kondo27, Daisuke Goto 27, Takayuki Sumida27, Naho Ayuzawa28, Hidetoshi Yanagida28, Tetsuya Horita29, Tatsuya Atsumi29, Hirahito Endo30, Yoshihito Shima31, Atsushi Kumanogoh31, Jun Hirata32, Nao Otomo1, Hiroyuki Suetsugu1, Yoshinao Koike1, Kohei Tomizuka1, Soichiro Yoshino1, Xiaoxi Liu1, Shuji Ito1, Keiko Hikino1, Akari Suzuki33, Yukihide Momozawa34, Shiro Ikegawa35, Yoshiya Tanaka10, Osamu Ishikawa11, Kazuhiko Takehara9, Takeshi Torii36, Shinichi Sato3, Yukinori Okada32, Tsuneyo Mimori12,37, Fumihiko Matsuda38, Koichi Matsuda39,40, Tiffany Amariuta41,42,43,44,45, Issei Imoto 46, Keitaro Matsuo47, Masataka Kuwana5, Yasushi Kawaguchi48, Koichiro Ohmura12, Chikashi Terao1,16,17 (1.RIKEN, Center for Integrative Medical Sciences, Laboratory for Statistical and Translational Medicine, Yokohama, Japan, 2.Tohoku University, Graduate School of Medicine, Department of Dermatology, Sendai, Japan, 3.The University of Tokyo, Department of Dermatology, Tokyo, Japan, 4.Chukyo Hospital, Japan Community Health Care Organization, Department of Dermatology, Nagoya, Japan, 5.Nippon Medical School Graduate School of Medicine, Department of Allergy and Rheumatology, Tokyo, Japan, 6.Kyushu University, Faculty of Medicine, Department of Medicine and Biosystemic Science, Fukuoka, Japan, 7.Department of Rheumatology, Saga University Hospital, Saga, Japan, 8. Faculty of Medical Sciences, University of Fukui, Department of Dermatology, Fukui, Japan, 9.Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Department of Molecular Pathology of Skin, Faculty of Medicine, Kanazawa, Japan, 10. School of Medicine, University of Occupational and Environmental Health, The First Department of Internal Medicine, Kitakyushu, Japan, 11.Gunma University Graduate School of Medicine, Department of Dermatology, Maebashi, Japan, 12.Department of Rheumatology and Clinical immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 13. Aichi Cancer Center Research Institute, Division of Molecular Genetics, Nagoya, Japan, 14. Tokyo Women's Medical University, Adachi Medical Center, Tokyo, Japan , 15. Department of Molecular Life Sciences, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Isehara, Japan, 16.Shizuoka General Hospital, The Clinical Research Center, Shizuoka, Japan, 17.School of Pharmaceutical Sciences, University of Shizuoka, The Department of Applied Genetics, Shizuoka, Japan, 18.Faculty of Medical Sciences, University of Fukui, Department of Dermatology, Fukui, Japan, 19.Wakayama Medical University Graduate School of Medicine, Department of Dermatology, Wakayama, Japan, 20.Faculty of Life Sciences, Kumamoto University, Department of Dermatology and Plastic Surgery, Kumamoto, Japan, 21.IMSUT Hospital, The Institute of Medical Science, The University of Tokyo, Department of Rheumatology and Allergy, Tokyo, Japan, 22. Sapporo Medical University School of Medicine, Department of Rheumatology and Clinical Immunology, Sapporo, Japan, 23.Nagoya City University Graduate School of Medical Sciences, Department of Geriatric and Environmental Dermatology, Nagoya, Japan, 24. Okazaki City Hospital, Department of Dermatology, Okazaki, Japan, 25.Fukushima Medical University, School of Medicine, Department of Dermatology, Fukushima, Japan, 26. Graduate School of Medicine, Osaka University, Department of Dermatology, Osaka, Japan, 27.Faculty of Medicine, University of Tsukuba, Department of Internal Medicine, Tsukuba, Japan, 28.National Hospital Organization, Utano National Hospital, Department of Clinical Immunology, Kyoto, Japan, 29.Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Department of Rheumatology, Endocrinology and Nephrology, Sapporo, Japan, 30.Omori Medical Center, Toho University, Rheumatic Disease Center, Tokyo, Japan, 31.Graduate School of Medicine, Osaka University, Department of Respiratory Medicine and Clinical Immunology, Osaka, Japan, 32.Immunology Frontier Center, Osaka University, Statistical Immunology, Osaka, Japan, 33.RIKEN Center for Integrative Medical Sciences, The Laboratory for Autoimmune Diseases, Yokohama, Japan, 34.RIKEN Center for Integrative Medical Sciences, The Laboratory for Genotyping Development, Yokohama, Japan, 35.RIKEN Center for Integrative Medical Sciences, The Laboratory for Bone and Joint Diseases, Yokohama, Japan, 36.Torii Clinic, Maizuru, Japan, 37.Ijinkai Takeada General Hospital, Kyoto, Japan, 38.Graduate School of Medicine, Kyoto University, Center for Genomic Medicine, Kyoto, Japan, 39.Institute of Medical Science, The University of Tokyo, Laboratory of Genome Technology, Human Genome Center, Tokyo, Japan, 40.Graduate School of Frontier Sciences, The University of Tokyo, Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Tokyo, Japan, 41.Center for Data Sciences, Harvard Medical School, Boston, MA, USA, 42.Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA, 43.Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA, 44.Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA, 45.Graduate School of Arts and Sciences, Harvard University, Cambridge, MA, USA, 46.Aichi Cancer Center Research Institute, Nagoya, Japan, 47.Aichi Cancer Center Research Institute, Division of Cancer Epidemiology and Prevention, Nagoya, Japan, 48.Tokyo Women's Medical University, Division of Rheumatology, Department of Internal Medicine, Tokyo, Japan)

[OE7-3]Genetic correlation analysis provides novel insight into genetic background of human traits centralizing psoriasis

Kotaro Ogawa1,2, Tsoi Lam3, Hiroaki Tanaka4, Masahiro Kanai5, Stuart Philip3, Nair Rajan3, Yoshiya Tanaka4, Hideki Mochizuki2, Elder James3, Yukinori Okada1,6,7,8 (1.Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan, 2.Department of Neurology, Osaka University Graduate School of Medicine, Suita, Japan, 3.University of Michigan Medical School, Ann Arbor, MI, USA., 4.The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan, 5.Broad Institute of MIT and Harvard, USA, 6.Department of Genome Informatics, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan, 7.Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan, 8.Laboratory of Statistical Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan)

[OE7-4]Genetic signatures of assortative mating in the Japanese population

Kenichi Yamamoto1,2, Kyuto Sonehara1, Shinichi Namba1, Takahiro Konuma1, Hironori Masuko3, Satoru Miyawaki4, The Biobank Japan Project5, Yoichiro Kamatani6, Nobuyuki Hizawa3, Keiichi Ozono1, Loic Yengo7, Yukinori Okada1,2,4,8 (1.Osaka University Graduate School of Medicine, Suita, Japan, 2.Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan, 3.Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, 4.Graduate School of Medicine, the University of Tokyo, Tokyo, Japan, 5.The Biobank Japan Project, 6.Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan, 7.Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia, 8.RIKEN Center for Integrative Medical Sciences, Yokohama, Japan)