[2S01m] 10. ASPIRE - Part 4

11:21 AM - 11:36 AM JST(2:21 AM - 2:36 AM UTC)

[2ASPR-06] Organic Semiconducting Hydrogel with Integrated Microbes and Enzymes for Selective Solar CO2 Conversion

○Glenn Quek¹ (1. Yusuf Hamied Department of Chemistry, University of Cambridge (UK))

Keywords:

organic semiconductors,hydrogels,biohybrids,semi-artificial photosynthesis

Integrating synthetic light-harvesting materials with biological CO2-fixing catalysts offers a promising route to efficient and selective solar-to-chemical conversion under mild conditions. However, progress remains limited by the lack of photocatalytic materials that combine biocompatibility, strong electronic coupling with biocatalysts, high biocatalyst loading capacity, and facile product separation. Here we introduce an organic semiconducting hydrogel synthesized from a rationally designed conjugated polyelectrolyte that is visible-light-absorbing, water-processable, and covalently cross-linkable. The resulting macroporous, positively charged hydrogel scaffold immobilizes both microbes and enzymes, promoting intimate abiotic–biotic interactions across the three-dimensional hydrogel matrix. This platform supports two distinct modes of sacrificial CO2 reduction: mediated electron transfer via photogenerated H2 to drive acetate synthesis in the microbe Clostridium ljungdahlii, and direct electron transfer from photoexcited polymer domains to the enzyme formate dehydrogenase for formate synthesis. By coupling the molecular programmability of organic semiconductors with the selectivity of biocatalysts, this work establishes a versatile class of soft biohybrid materials for solar fuel production through semi-artificial photosynthesis.