[3S02m] 05. Genome Editing Technology and its Applications - Part 1

11:10 AM - 11:25 AM JST(2:10 AM - 2:25 AM UTC)

[3GET-05] TRU-PE: A Universal, Trackable Prime Editor Toolkit for Robust Single- and Multi-Locus Genome Engineering

○Zhuobin Liang¹, Zhichao Qiu^1,2,3, Keke Sun^1,4, Qingwei Zeng¹, Ziwei Luo^1,5, Xinran Liu¹, Yaping Li¹, Xiang Lei¹, Ruilin Zhao^1,6, Zhen Zhang^1,7, Damia Romero-Moya², Yuan Yang^2,3,8, Xuan Wang¹, Ehsan Hashemi¹, Joe Z. Zhang⁸, Xiaolong Wang⁴, Alessandra Giorgetti^2,3 (1. Institute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen, Guangdong, 518132 (China), 2. Regenerative Medicine Program, Bellvitge Institute for Biomedical Research (IDIBELL) and Program for Clinical Translation of Regenerative Medicine in Catalonia (P-CMRC), Barcelona, 08908 (Spain), 3. Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, Barcelona University, Barcelona, 08907 (Spain), 4. Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100 (China), 5. Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, 3000 (Australia), 6. Department of Life Sciences and Biochemistry, Faculty of Arts and Science, Queen's University, Kingston, Ontario, K7L3N6 (Canada), 7. School of Science, Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong, 518107 (China), 8. Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, Guangdong, 518132 (China))

Keywords:

Genome engineering,Prime Editing,Disease Modeling,iPSC,GATA2 deficiency

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