Artificial Intelligence and Data-Driven Approaches in Flow Chemistry 2

4:20 PM - 4:40 PM JST(7:20 AM - 7:40 AM UTC)

[q2Trbfo6-01] A Multi-Fidelity Framework for AI-Driven Optimisation and Scale-Up of RNA Nanomedicines: from Proxy to Production

*Roisin O'Connell¹, Stephen Knox², Peter Pittaway¹, Kudakwashe Chingono¹, Mostafa Soroor¹, Arwen Tyler¹, Georgia Maitland⁴, Matthew Derry⁴, Paul Topham⁴, Martha Ilett¹, Nicole Hondow¹, Nga Vo³, Libby Forster³, Connie Smith³, George Panoutsos², John Oyekan⁵, Nikil Kapur¹, Richard Bourne¹, Thomas Chamberlain¹, Nicholas Warren^1,2 (1. University of Leeds (UK), 2. University of Sheffield (UK), 3. CPI (UK), 4. Aston University (UK), 5. University of York (UK))

Keywords:

Lipid Nanoparticles,Closed-loop optimisation,Machine learning,Flow platform,Scale-up