The 79th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery
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SymposiumCardiac

[CSY2]Cardiac Symposium 2　Translational Advances in Cardiothoracic Surgery：The Role of Large Animal Models in Biomedical Innovation

Tue. Oct 20, 2026 8:00 AM - 9:30 AM JST
Tue. Oct 20, 2026 11:00 PM - 12:30 AM UTC
Room 3 (Room B‒1, 2F, Kyoto International Conference Center)
Chairperson: Hidetoshi Masumoto（Department of Cardiovascular Surgery, Kansai Medical University）, Daisuke Onohara (The Ohio State University College of Medicine/Research Institute at Nationwide Children's Hospital, USA)

[CSY2-1]Significance of Large Animal Experiments in Thoracic Surgery and the Need to Maintain Research Infrastructure

Hisashi Sahara (Life Science and Laboratory Animal Research Unit, Division of Experimental Large Animal Research, Center for Advanced Science Research and Promotion, Kagoshima University)

[CSY2-2]The Role of Large Animal Models in Translational Therapeutic Development for Cardiovascular Surgery: Practical Experience from the United States

Daisuke Onohara1,2, Kosuke Nakamae1, Chihiro Miyagi1, Tatsuya Watanabe1, Jyunya Matsuda1, Syed Hussaini1, Satoshi Yuhara1 (1.Center for Regenerative Medicine, Research Institute at Nationwide Children's Hospital, USA, 2.Department of Pediatrics, The Ohio State University College of Medicine, USA)

[CSY2-3]Large Animal Research in the Field of Thoracic Surgery

Toyofumi Fengshi Chen-Yoshikawa (Deapartment of Thoracic Surgery, Kyoto University and Nagoya University)

[CSY2-4]Development of a Large Animal Model for Implantable Artificial Lung Research: From Pulmonary Artery-Left Atrium Central ECMO Model to an Anterior Lobectomy-Based Intrathoracic Space-Creating Model

Masaki Anraku1,2, Takashi Isoyama3, Hiromichi Asahina4, Ziyue Zhang3, Shintaro Hara5, Kento Fukumoto2, Keita Nakao2, Yuya Nobori2, Koji Aze1,2, Riku Kobashi6, Kazuaki Sato6, Fumikazu Watanabe6, Hiroaki Oshiyama7, Masaaki Sato2, Minoru Ono4, Jun Nakajima2,8 (1.Department of Thoracic Surgery, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 2.Department of Thoracic Surgery, the University of Tokyo Hospital, 3.Department of Clinical Engineering, Kyorin University, 4.Department of Cardiac Surgery, the University of Tokyo Hospital, 5.Department of Clinical Engineering, Tokyo Women's Medical University, 6.Fuji Systems Co., Ltd., 7.Terumo Corporation, 8.Department of Thoracic Surgery, Japanese Red Cross Medical Center)

[CSY2-5]Large Animal Studies for Medical Device Commercialization: Developing a Class IV Cardiovascular Patch with Autologous Tissue Ingrowth and Fair Value-Based Reimbursement Strategies

Shintaro Nemoto, Hayato Konishi, Akiyo Suzuki, Takahiro Katsumata (Department of Thoracic and Cardiovascular Surgery, Osaka Medical and Pharmaceutical University)

[CSY2-6]The Role of Large Animal Models in the Clinical Translation of iPSC-Derived
Cardiomyocyte Sheets and Regulatory Frameworks for Regenerative Medicine
Products

Shigeru Miyagawa (Cardiovascular Surgery, Department of Surgery, Graduate School of Medicine, The University of Osaka)
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