[G] Fundamentals of Biomaterials and Bio-responses

5:10 PM - 5:25 PM JST(8:10 AM - 8:25 AM UTC)

[162] Assessing Biological Impacts of Low-Density Polyethylene Nanoplastics with an In Vitro Blood-Brain Barrier Model

*Yuji ZHAO¹, mako Kobayashi¹, naoto Washihira¹, sho Fujii², tadao Tanabe³, tsuyoshi Kimura⁴, masaya Yamamoto^1,5 (1. Grad. Sch. Eng., Tohoku Univ, 2. Sch. Sci., Yamagata Univ, 3. Sch. Eng. Des., Shibaura Inst. Technol, 4. Sch. Biomed. Eng., Toyo Univ, 5. Grad. Sch. of Biomed. Eng., Tohoku Univ)

Keywords:

Blood-Brain Barrier,Nanoplastics,Biological Evaluation

酸化処理を施したLDPEナノプラスチックを用い、dECMコーティングを施したin vitro血液脳関門モデルでその透過性と生体影響を評価し、モデルの有効性を示した