General information

Announcements(2)

Program

Sessions

Search presentations

Download PDF for print

Timetable

Mon. Mar 16, 2026

Tue. Mar 17, 2026

Wed. Mar 18, 2026

web_header.png

web_icon.png

Change account information such as the email address and password on the account setting screen common to Confit.

Login required to view

Password required to view

Presentation Information

Session Details

Enter the password to view the abstracts.<br>The password will be emailed to those who have completed the registration.

To browse or post comments, you must log in.

You cannot post comments as it is outside the comment posting period.

This comment has been deleted. You cannot reply to this comment.

Program Type

Announcements

Profile management

Bookmark

Exploring common pathogenic mechanisms in spinocerebellar ataxias, beginning with PKC research

Protein kinase C (PKC) is a serine/threonine kinase first identified in 1977 by Dr. Yasumi Nishizuka, then a professor at Kobe University. More than ten distinct molecular isoforms are expressed across various tissues, and their roles in a wide range of physiological processes have been extensively characterized. Although PKC was historically regarded as a prototypical oncogenic factor, subsequent paradigm shifts have redefined it as a potential tumor suppressor. In the nervous system, PKC modulates long-term potentiation and depression, thereby contributing to synaptic plasticity. Moreover, its potential involvement in neurodegenerative disorders, including spinocerebellar degeneration and Alzheimer disease, has been proposed. This symposium seeks to present the historical development and current advances in PKC research, with particular emphasis on its regulatory mechanisms and physiological functions elucidated through imaging-based approaches, and to explore prospective therapeutic applications.

The 99th Annual Meeting of the Japanese Pharmacological Society

Presentation Information

[1-S-17]Exploring common pathogenic mechanisms in spinocerebellar ataxias, beginning with PKC research

Keywords:

Password required to view

Comment