Presentation Information

[3-P-047]Rotenone-induced SPARC secretion from astrocytes promotes dopaminergic neurodegeneration

*Ikuko Miyazaki1, Nami Isooka1, Ryo Kikuoka1,2, Fuminori Imafuku1, Kaori Masai1, Kana Tomimoto1, Masakiyo Sakaguchi3, Chiharu Sogawa4, Norio Sogawa1,5, Yoshihisa Kitamura6, Masato Asanuma1 (1. Dept. of Med. Neurobiol., Okayama Univ. Grad. Sch. of Med., Dent. and Pharmaceut. Sci., 2. Dept. of Pharm., Okayama Univ. Hosp., 3. Dept. of Cell Biol., Okayama Univ. Grad. Sch. of Med., Dent. and Pharmaceut. Sci., 4. Dept. of Food and Health Sci., Fac. of Environment. Studies, Hiroshima Inst. of Tech., 5. Dept. of Mol. Eng. and Drug Dev. Sci., Grad. Sch. of Oral Med., Matsumoto Dental Univ., 6. Dept. of Pharmacother., Sch. of Pharm., Shujitsu Univ.)

Keywords:

astrocyte,microglia,parkinsonism,neurodegeneration

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