Presentation Information
[2I5-OS-7a-03]Determining Re-examination Criteria in Biochemical Testing Using Mathematical Optimization
〇Keisuke Onoue1,3, Ryosuke Kojima1,4,5, Tomokazu Kitamura1, Nozomi Yamasaki2, Atsuko Nishihara2 (1. Scrum Sign Inc., 2. Department of Clinical Laboratory, Kuma Hospital, 3. Nara Institute of Science and Technology, 4. Graduate School of Medicine, Kyoto University, 5. RIKEN Center for Biosystems Dynamics Research)
Keywords:
Mathematical Optimization,Biochemical Testing
Re-examination in clinical chemistry testing is a critically important process for ensuring the reliability of test results and maintaining patient safety.
However, re-examination criteria have largely depended on individual experience, and quantitative standards have not yet been sufficiently established.
In this study, aiming to improve the efficiency of re-examination, we applied a mathematical optimization approach based on historical laboratory data to optimize re-examination thresholds and implemented them in the laboratory information system (LIS).
Simulation using approximately 400,000 clinical test records demonstrated that the excessive alert rate, which had previously exceeded 60\%, could be precisely controlled to 15\%, a level considered operationally appropriate.
The introduction of these standardized internal re-examination criteria was shown to enhance the objectivity of re-examination decisions while contributing to a reduction in technologist workload and the optimization of laboratory quality management.
However, re-examination criteria have largely depended on individual experience, and quantitative standards have not yet been sufficiently established.
In this study, aiming to improve the efficiency of re-examination, we applied a mathematical optimization approach based on historical laboratory data to optimize re-examination thresholds and implemented them in the laboratory information system (LIS).
Simulation using approximately 400,000 clinical test records demonstrated that the excessive alert rate, which had previously exceeded 60\%, could be precisely controlled to 15\%, a level considered operationally appropriate.
The introduction of these standardized internal re-examination criteria was shown to enhance the objectivity of re-examination decisions while contributing to a reduction in technologist workload and the optimization of laboratory quality management.