Presentation Information

[2Yin-A-27]Long-Context Modeling and Physiological Constraints for ECG Generation from PPG

〇So Kariyama1,3, Kazuyuki Yoshikawa2,3, Mika Akama3, Nayuta Mizuguchi1,3 (1. The University of Tokyo, 2. University of Hyogo, 3. FastNeura Inc.)

Keywords:

Physiological Signal Generation,Conditional Generative Models,Electrocardiogram (ECG),Photoplethysmogram (PPG)

Generating electrocardiograms (ECGs) from wearable photoplethysmograms (PPGs) can enable low-cost and continuous cardiac monitoring, but existing PPG-to-ECG generators often reproduce waveform shapes while failing to preserve beat timing. We propose a two-stage RR-conditioned Rectified Flow framework for long-context ECG generation from PPG. In Stage A, a lightweight CNN predicts an RR-interval signal from PPG using differentiable rhythm-consistency losses. In Stage B, the predicted RR signal is frozen and provided as an additional condition to a Rectified Flow generator with a 1D U-Net backbone, enabling explicit control of beat timing without relying on non-differentiable peak-based losses during training. Experiments on the PPG-DaLiA dataset with 30 s and 60 s windows show that the proposed method improves HR MAE by 55-67% and RR MAE by 14-30% over a baseline, while maintaining waveform RMSE and PSD similarity. HRV improvements remain limited, indicating the need for better R-wave morphology modeling.