[17p-C32-1~13] 12.6 Nanobiotechnology

2:30 PM - 2:45 PM JST(5:30 AM - 5:45 AM UTC)

[17p-C32-6] Identifying genome-derived difference in vector characteristics by nanopore sensing

〇Makusu Tsutsui¹, Mikako Wada², Akihide Arima³, Yuji Tsunekawa², Takako Sasaki², Kazumichi Yokota⁴, Yoshinobu Baba³, Tomoji Kawai¹, Takashi Okada² (1.Osaka Univ., 2.Univ. Tokyo, 3.Nagoya Univ., 4.AIST)

Keywords:

nanopore,viral vector,ionic current

This study reports single-particle discriminations of empty, intermediate, and full adeno-associated virus vectors by their minute difference in the particle sizes through ionic current measurements using a solid-state nanopore.