[18p-B2-1~15] 4.6 Terahertz Photonics

6:00 PM - 6:15 PM JST(9:00 AM - 9:15 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation AwardEnglish Presentation

[18p-B2-15] Kinetics analysis of anti-CD9 antibody and H1299 EV using terahertz chemical microscope

〇(M2)YUCHEN MA¹, Changjiang Liu¹, Xue Ding¹, Jin Wang¹, Toshihiko Kiwa¹ (1.Okayama Univ.)

Keywords:

THz systems

In recent years, hospitals have used PET-CT scans and pathology to detect lung cancer, but PET-CT scans involve the use of radioactive tracers as well as X-rays from the CT scan, frequent scans can increase long-term health risks, and pathology requires advanced technology. Recent studies have shown that exosomes released from cells can provide the information needed to detect and diagnose cancer. Exosomes play an important role in tumourigenesis, cancer invasion, angiogenesis, tumour microenvironment formation and cancer metastasis. Currently, exosome detection methods include SPR and ELISA, but both have limitations and cannot quickly detect small samples. To address these problems, our research group developed terahertz chemical microscope (TCM) [1,2,3]. Through TCM detection, we found that the concentration of exosomes is proportional to the intensity of terahertz waves. This demonstrates TCM can be used for the quantitative analysis of exosomes.