[18p-C32-1~12] 12.6 Nanobiotechnology

1:00 PM - 1:15 PM JST(4:00 AM - 4:15 AM UTC)

[18p-C32-1] Interaction of Triacylglycerol Droplets with Giant Unilamellar Vesicles: Induction of Bilayer Spontaneous Curvature

〇Chiho Kataoka¹ (1.NIMS)

Keywords:

phospholipids,giant unilamellar vesicles,triacylglycerols

When an intracellular lipid droplet generates in an endoplasmic reticulum (ER) membrane, triacylglycerol (TAG) droplets are embedded between the phospholipid monolayers of the ER membrane. To understand this bilayer structure, we incorporated TAG droplets in giant unilamellar vesicle (GUV) bilayers. In addition to GUVs with droplets, we often observed a vesicle consisting of a single-bilayer spherical segment and a double-bilayer spherical segment. In the presentation, we discuss the reason of the formation of these vesicles.