[20p-A33-1~13] 8.4 Plasma life sciences

1:30 PM - 1:45 PM JST(4:30 AM - 4:45 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[20p-A33-1] Effect of atmospheric pressure oxygen plasma on the immune response of inflammatory macrophages

〇Saori Kodaka¹, Yoshihito Yagyu¹, Nobuya Hayashi¹, Reona Aijima², Yoshio Yamashita² (1.Kyushu Univ., 2.Saga Univ.)

Keywords:

atmospheric pressure oxygen plasma,macrophage,cytokine

The authors focus on macrophages, which play an important role, and attempt to induce differentiation into M1 macrophages, which enhance their attack on pathogens, by atmospheric pressure oxygen plasma irradiation. From previous studies, it was found that plasma irradiation and the addition of T cell supernatant can also obtain effects other than phagocytosis. Therefore, in this study, we investigated the effect of plasma irradiation on cytokine production and other functions of a system simulating a macrophage-T cell coexistence system by measuring the amount of ROS and NO.