Presentation Information
[10a-N104-2]Computational aberration correction and de-speckling for high-resolution, high-speed optical coherence tomography volumetric retinal imaging
〇Shuichi Makita1, Wang Xibo1, Komeda Suzuyo1, Yoshiaki Yasuno1 (1.COG, Univ. Tsukuba)
Keywords:
optical coherence tomography,aberration,speckle supression
Optical coherence tomography (OCT) is a non-invasive high-resolution volumetric imaging modality.
OCT is used for diagnosis and investigation and treatments of in vivo human retina.
However, its spatial resolution is usually not high for cellular imaging.
The lateral resolution of OCT is limited by ocular aberrations and speckle.
Both have been addressed by computational methods in this study.
Degradations of lateral resolution by de-focus and high-order ocular aberrations are compensated by an aberration correction deconvolution filter based on bi-pupil OCT image formation theory.
The computational speckle suppression is derived from the random scatterer model and applied.
We have achieved high-resolution imaging of the human retina in vivo without the need for hardware correction or multiple acquisitions.
OCT is used for diagnosis and investigation and treatments of in vivo human retina.
However, its spatial resolution is usually not high for cellular imaging.
The lateral resolution of OCT is limited by ocular aberrations and speckle.
Both have been addressed by computational methods in this study.
Degradations of lateral resolution by de-focus and high-order ocular aberrations are compensated by an aberration correction deconvolution filter based on bi-pupil OCT image formation theory.
The computational speckle suppression is derived from the random scatterer model and applied.
We have achieved high-resolution imaging of the human retina in vivo without the need for hardware correction or multiple acquisitions.