[7p-N305-1~18] 12.7 Biomedical Engineering and Biochips

2:45 PM - 3:00 PM JST(5:45 AM - 6:00 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation AwardEnglish Presentation

[7p-N305-6] Lens-Free CMOS Microimaging Device with Diffractor Pattern for Improving Fluorescence Imaging

〇(D)Arphorn Promking¹, Yoshinori Sunaga¹, Yasumi Ohta¹, Ryoma Okada¹, Hironari Tashiro^1,2, Jun Ohta¹, Kiyotaka Sasagawa¹ (1.NAIST, 2.Kyushu University)

Keywords:

Lens-free CMOS microimaging device,A diffractor pattern,Fluorescence Imaging

A lens-free CMOS microimaging device has been developed to observe brain activity with animals moving freely. This thin device can be implanted on the surface and deep in the mouse's brain. However, the lack of a lens and uneven LED excitation light pose challenges in producing a high-quality fluorescent image. Recently, we successfully enhanced fluorescent imaging contrast by proposing a diffractor pattern with a hybrid filter in a lensless commercial CMOS image sensor. This revealed the light source directs to the target in the same direction as an image sensor, like epifluorescence imaging.
In this study, a diffractor pattern was implemented in the lens-free CMOS microimaging device, and a waterproof layer was sealed around that pattern.