Presentation Information

[7p-N306-12]Correlation between morphological and surface molecular distributions of extracellular vesicles

〇Sou Ryuzaki1, Yuki Komoto2, Keisuke Imaeda1, Kosei Ueno1, Masateru Taniguchi2 (1.Dept. Chem., Fac. Sci., Hokkaido Univ., 2.SANKEN. Osaka Univ.)

Keywords:

Extracellular vesicles

Extracellular vesicles (EVs) are lipid bilayer particles with diameters ranging from 40 to 200 nm, containing microRNAs internally and diverse molecules on their surface. Their chemical and physical properties are valuable for cancer detection and characterization, highlighting the importance of single-particle analysis. In this presentation, we report the chemical and physical characteristics of EVs derived from HepG2, MDA-MB-231, and HCT116 cells, as well as the correlations between these features, as revealed by nanopore-based analysis.