[8p-E311-1~19] 8.4 Plasma life sciences

1:45 PM - 2:00 PM JST(4:45 AM - 5:00 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[8p-E311-2] Biofunctionalization of hydrophobic substrate using plasma-treated collagen solution

〇Ryosuke Watanabe¹, Ayano Goto¹, Yoshikazu Hattori², Noriyuki Uchida¹, Masaki Okumura³, Takahiro Muraoka¹, Tomohide Saio², Daisuke Yoshino¹ (1.TUAT, 2.Tokushima Univ., 3.Tohoku Univ.)

Keywords:

Surface discharge,Surface modification,Biomaterials

Toward the biofunctionalization of biomaterial surfaces, this study investigated a new biointerface formation method involving plasma treatment of a biopolymer solution before coating, rather than treatment of the substrate itself. Type I collagen solution was treated using a surface discharge device, and its coating behavior on hydrophobic substrates and cell adhesion were evaluated. The plasma-treated collagen solution formed a fine, continuous film and enhanced HUVEC adhesion. These results suggest that charge supply to the solution and changes in the collagen association state cooperatively contributed to the biofunctionalization of hydrophobic substrates.