[8p-E311-1~19] 8.4 Plasma life sciences

2:15 PM - 2:30 PM JST(5:15 AM - 5:30 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[8p-E311-4] Cell proliferation-promoting effects and intracellular uptake of oxygen radical-treated tryptophan derivative solutions

〇(M2)Takashi Eto¹, Daiji Kitagawa², Hiromasa Tanaka², Kenji Ishikawa², Masaru Hori², Masafumi Ito¹ (1.Meijo Univ., 2.Nagoya Univ.)

Keywords:

Plasma,Cell,Oxygen radicals

Recently, we have reported that N’-formylkynurenine (NFK), produced by irradiating tryptophan (Trp) with oxygen radicals, can be converted with very high efficiency, 89.5% for NFK and 10.2% for kynurenine (KYN), for a total yield of 99.7% and that these compounds promote fibroblast proliferation.
In this study, we indirectly evaluated the synergistic effects of these derivatives on fibroblast uptake and proliferation.