[9a-C309-1~13] 12.7 Biomedical Engineering and Biochips

11:45 AM - 12:00 PM JST(2:45 AM - 3:00 AM UTC)

[9a-C309-11] Development of a Digital Bioanalysis Platform: Clinical Application of SATORI Method

〇Tatsuya Iida¹, Hajime Shinoda¹, Rikiya Watanabe¹ (1.RIKEN)

Keywords:

single-molecule digital bioanalysis,CRISPR-Cas,infectious disease diagnostics

Toward point-of-care testing for infectious diseases, we developed COWFISH2A+, a benchtop device that automates SATORI, which combines CRISPR-Cas13a with digital bioanalysis on microchamber chips. Clinical specimen evaluation targeting SARS-CoV-2 and influenza A/B demonstrated its utility for rapid and sensitive diagnostics, as well as its potential as a versatile digital bioanalysis platform.