Presentation Information

[9p-E310-8]Watching Molecules in Motion: High-Speed AFM Imaging from Biomolecules to Synthetic Polymers and Supramolecular Systems

〇Takayuki Uchihashi1 (1.Nagoya Univ.)

Keywords:

high-speed atomic force microscopy,single-molecule imaging

High-speed atomic force microscopy (HS-AFM) has made it possible to watch single biomolecules in action, capturing working proteins as real-time movies at nanometer and sub-second resolution. Over the past two decades, this has opened a new frontier in molecular life science, revealing how biological machines move and function. More recently, HS-AFM imaging has expanded well beyond biomolecules: synthetic polymers and supramolecular systems are now observed in motion, from polymer crystallization to the self-assembly of supramolecular architectures. In this talk, I will trace the evolution of HS-AFM imaging—from its origins in biology to its current expansion into synthetic and supramolecular chemistry—and discuss where this technique is headed, highlighting how watching molecules in motion keeps opening new windows onto nanoscale dynamics.