Presentation Information

[3E-122]Identification of the novel TFEB target regulating initial step of PINK1/Parkin-dependent mitophagy

*Mengying Cui1, Satoshi Minami1, Waka Kojima2,3,4, Koji Yamano2, Hidesato Ogawa5, Noriyuki Matsuda2,6, Shuhei Nakamura1,7,8, Tamotsu Yoshimori1,7,9 (1. Department of Genetics, Graduate School of Medicine, Osaka University, Osaka, Japan, 2. Ubiquitin Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan, 3. Laboratory of Protein Metabolism, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan, 4. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, the University of Tokyo, Kashiwa, Japan, 5. Laboratory of Nuclear Dynamics Group, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan, 6. Biomolecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan, 7. Department of Intracellular Membrane Dynamics, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan, 8. Institute for Advanced Co-Creation Studies, Osaka University, Osaka, Japan, 9. Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, Osaka, Japan)

Keywords:

TFEB,mitophagy,autophagy,PINK1,Parkin

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