Presentation Information
[E5-4]Effectiveness of Flavonoids in Postoperative Pain and Wet Anus After Hemorrhoidectomy
Waranthorn Somjinda, Siripong Sirikurnpiboon (Department of Surgery, Rajavithi Hospital)
Background: Hemorrhoidectomy is the standard treatment for symptomatic or high-grade hemorrhoids; however, complications such as postoperative pain, wound dehiscence, and wet anus are common. Wet anus significantly impacts patient comfort and hygiene but remains understudied.
Objective: To evaluate the effectiveness of flavonoids in reducing postoperative pain and the incidence of wet anus.
Methods: A retrospective cohort study was conducted in 180 patients who underwent hemorrhoidectomy between 2017 and 2022. Patients were divided into a flavonoid group (n = 91) and a control group (n = 89). Postoperative outcomes including pain scores, wet anus, pruritus ani, acetaminophen consumption, and complications were analyzed.
Results: The incidence of wet anus was significantly lower in the flavonoid group (18.7% vs. 67.4%, p<0.001), as was pruritus ani (18.7% vs. 56.2%, p<0.001). Pain scores at 6 hours postoperatively were similar (7.22 vs. 7.25, p = 0.891), but the next-morning scores were modestly lower in the flavonoid group (6.11 vs. 6.73, p = 0.017). Acetaminophen consumption was significantly lower in the flavonoid group (1069.6 mg vs. 1631.6 mg, p<0.001). Wound dehiscence was also less frequent (16.5% vs. 25.8%, p = 0.045; OR = 0.473, 95% CI: 0.2260.993).
Conclusion: Flavonoids significantly reduced the incidence of wet anus and pruritus ani, and may lower the need for analgesics and wound complications. These findings support the adjunctive use of flavonoids in postoperative care following hemorrhoidectomy.
Objective: To evaluate the effectiveness of flavonoids in reducing postoperative pain and the incidence of wet anus.
Methods: A retrospective cohort study was conducted in 180 patients who underwent hemorrhoidectomy between 2017 and 2022. Patients were divided into a flavonoid group (n = 91) and a control group (n = 89). Postoperative outcomes including pain scores, wet anus, pruritus ani, acetaminophen consumption, and complications were analyzed.
Results: The incidence of wet anus was significantly lower in the flavonoid group (18.7% vs. 67.4%, p<0.001), as was pruritus ani (18.7% vs. 56.2%, p<0.001). Pain scores at 6 hours postoperatively were similar (7.22 vs. 7.25, p = 0.891), but the next-morning scores were modestly lower in the flavonoid group (6.11 vs. 6.73, p = 0.017). Acetaminophen consumption was significantly lower in the flavonoid group (1069.6 mg vs. 1631.6 mg, p<0.001). Wound dehiscence was also less frequent (16.5% vs. 25.8%, p = 0.045; OR = 0.473, 95% CI: 0.2260.993).
Conclusion: Flavonoids significantly reduced the incidence of wet anus and pruritus ani, and may lower the need for analgesics and wound complications. These findings support the adjunctive use of flavonoids in postoperative care following hemorrhoidectomy.