Presentation Information
[INTS1-1]Predisposing Factors and Clinical Outcomes of Patients with Fournier’s Gangrene in a Government Tertiary Hospital
*Ernes John Talingdan Castro1, Clint Charl Tan Malaluan1, Andrei Cesar Sanares Abella1 (1. Section of Colorectal Surgery, Batangas Medical Center, Philippines)
Purpose:
This study aimed to describe the clinico-demographic profile and clinical outcomes of patients diagnosed with Fournier’s Gangrene (FG) at a government tertiary hospital. The study also evaluated the prognostic factors related with survival of patients with FG.
Methods:
This is a retrospective chart review that analyzed all FG cases from 2018 up to 2024. Data collected included medical history, comorbidities, vital signs, laboratory parameters at admission. Antibiotic use was also obtained. Number of debridement, need for bowel/urinary diversion were noted. Fournier Gangrene Severity Index (FGSI) Scores were also computed. The data were analyzed in relation between survivors and non-survivors. Descriptive statistics, Mann-Whitney U test, chi- square test, Wilcoxon signed rank test were used to compare survivors and non-survivors, whichever was applicable.
Results:
A total of 61 patients were included for analysis. Majority of the patients were male (95.08%). Mean age was 54 years old. Mean Body Mass Index was 22.28, which was in the normal range. Diabetes mellitus was the most common comorbidity seen in these patients (62.3%). There was varied use of antibiotics, with a combination of Piperacillin-tazobactam and Vancomycin as the most common choice. Majority of patients (67.2%) underwent just one debridement, while the rest needed at least two debridement, with four as the most number done. Over-all mortality rate was 18.03%. When comparing survivors vs non-survivors, age and sex did not differ between the two groups. There were statistically significant differences between the two groups in Hematocrit (p=0.002), Creatinine (p=0.039), Bicarbonate (p=0.026), number of debridement (p=0.039) and FGSI scores (p=0.0003). There were no differences in White Blood Cell, Sodium, Potassium, need for bowel diversion, and hospital length of stay.
Conclusion:
Among patients with FG, low Hematocrit, high Creatinine, decreased Bicarbonate, and increased debridement were associated with higher mortality. FGSI scores were also higher in the non-survivor group.
This study aimed to describe the clinico-demographic profile and clinical outcomes of patients diagnosed with Fournier’s Gangrene (FG) at a government tertiary hospital. The study also evaluated the prognostic factors related with survival of patients with FG.
Methods:
This is a retrospective chart review that analyzed all FG cases from 2018 up to 2024. Data collected included medical history, comorbidities, vital signs, laboratory parameters at admission. Antibiotic use was also obtained. Number of debridement, need for bowel/urinary diversion were noted. Fournier Gangrene Severity Index (FGSI) Scores were also computed. The data were analyzed in relation between survivors and non-survivors. Descriptive statistics, Mann-Whitney U test, chi- square test, Wilcoxon signed rank test were used to compare survivors and non-survivors, whichever was applicable.
Results:
A total of 61 patients were included for analysis. Majority of the patients were male (95.08%). Mean age was 54 years old. Mean Body Mass Index was 22.28, which was in the normal range. Diabetes mellitus was the most common comorbidity seen in these patients (62.3%). There was varied use of antibiotics, with a combination of Piperacillin-tazobactam and Vancomycin as the most common choice. Majority of patients (67.2%) underwent just one debridement, while the rest needed at least two debridement, with four as the most number done. Over-all mortality rate was 18.03%. When comparing survivors vs non-survivors, age and sex did not differ between the two groups. There were statistically significant differences between the two groups in Hematocrit (p=0.002), Creatinine (p=0.039), Bicarbonate (p=0.026), number of debridement (p=0.039) and FGSI scores (p=0.0003). There were no differences in White Blood Cell, Sodium, Potassium, need for bowel diversion, and hospital length of stay.
Conclusion:
Among patients with FG, low Hematocrit, high Creatinine, decreased Bicarbonate, and increased debridement were associated with higher mortality. FGSI scores were also higher in the non-survivor group.