Session Details
[O11]Oral Session 11 Complex Disorders
Sat. Oct 12, 2024 9:00 AM - 9:50 AM JST
Sat. Oct 12, 2024 12:00 AM - 12:50 AM UTC
Sat. Oct 12, 2024 12:00 AM - 12:50 AM UTC
Room 4（Regent Hall, 2F）
Chairs：Tomoharu Tokutomi（Department of Pediatrics, Kawasaki Medical School）, Tomohiro Nakayama（Nihon University School of Medicine）
[O11-1]Identification of PTPN2 as a susceptibility locus for primary biliary cholangitis by genome-wide association study
○Yuki Hitomi1, Kazuko Ueno2, Yoshihiro Aiba3, Nao Nishida4, Michihiro Kono5, Mitsuki Sugihara6, Yosuke Kawai2, Minae Kawashima7, Seik-Soon Khor2, Kazuyoshi Ishigaki5, Masao Nagasaki6, Katsushi Tokunaga2, Nakamura Minoru3,8 (1.Department of Human Genetics, Research Institute, National Center for Global Health and Medicine, 2.Genome Medical Science Project, Research Institute, National Center for Global Health and Medicine, 3.Clinical Research Center, NHO Nagasaki Medical Center, 4.Department of Genomic Function and Diversity, Medical Research Institute, Tokyo Medical and Dental University, 5.Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, 6.Division of Biomedical Information Analysis, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, 7.Database Center for Life Science, Research Organization of Information and Systems, 8.Department of Hepatology, Nagasaki University Graduate School of Biomedical Sciences)
[O11-2]A conditional mutant strategy to unravel mysteries of lethal congenital disorders
○Sayuri Sakagami, Mukhamad Sunardi, Keisuke Ito, Toshihiro Uesaka, Hideki Enomoto (Division of Neural Differentiation and Regeneration, Kobe University Graduate School of Medicine, Hyogo, Japan)
[O11-3]Contribution of rare variants to heritability of a disease is much greater than conventionally estimated
○Yoshiro Nagao1,2 (1.Department of Clinical Genetics, Tokai University Hospital, Isehara, Japan, 2.Department of Laboratory Examination, Takashimadaira Chuo General Hospital)
[O11-4]Association analysis of HLA-DQB1 with narcolepsy type 2 and idiopathic hypersomnia
○Taku Miyagawa1, Mihoko Shimada1,2, Tohru Kodama1, Yoshiko Honda1, Katsushi Tokunaga2, Makoto Honda1,3 (1.Sleep Disorders Project, Department of Psychiatry and Behavioral Sciences, Tokyo Metropolitan Institute of Medical Science, 2.Genome Medical Science Project (Toyama), National Center for Global Health and Medicine (NCGM), 3.Japan Somnology Center and Seiwa Hospital)
[O11-5]Anxiety-like behaviors are increased in female mice by a CRHR2 variant identified in an eating disorder family
○Akira Oka1, Ayaka Nakamura2, Hiromi Miura1, Masato Ohtsuka1 (1.Department of Molecular Life Sciences, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, 2.The Support Center for Medical Research and Education, Tokai University)